0000000000286592

AUTHOR

Ernesto Zecca

0000-0003-1689-0370

showing 3 related works from this author

Comparison of octreotide and hyoscine butylbromide in controlling gastrointestinal symptoms due to malignant inoperable bowel obstruction

2000

In advanced cancer patients with inoperable bowel obstruction, the administration of antisecretive and antiemetic drugs has proved to be effective in controlling gastrointestinal symptoms caused by bowel obstruction. However, controlled studies concerning the most effective antisecretive drug are lacking. The aim of this randomized controlled study was to determine whether octreotide or hyoscine butylbromide was the more effective antisecretive drug for use in states of inoperable bowel obstruction. Eighteen patients with inoperable bowel obstruction randomly received octreotide 0.3 mg daily (n = 9) or hyoscine butylbromide (HB) 60 mg daily (n = 9) s.c. The following parameters were measure…

Malemedicine.medical_specialtyPalliative careNauseaScopolamineOctreotideMuscarinic AntagonistsOctreotideGastroenterologyHyoscine butylbromideStatistics Nonparametriclaw.inventionGastrointestinal AgentsRandomized controlled triallawInternal medicineNausea and vomitingmedicineHumansProspective StudiesProspective cohort studyNursing (all)2901 Nursing (miscellaneous)AgedCancerAged 80 and overGastrointestinal agentChi-Square Distributionbusiness.industryPalliative CareMiddle Agedmedicine.diseaseBowel obstructionTreatment OutcomeOncologyAbdominal NeoplasmsAnesthesiaVomitingFluid TherapyFemalemedicine.symptombusinessIntestinal Obstructionmedicine.drugBowel obstruction
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Role of Octreotide, Scopolamine Butylbromide, and Hydration in Symptom Control of Patients with Inoperable Bowel Obstruction and Nasogastric Tubes

2000

Bowel obstruction may be an inoperable complication in patients with end-stage cancer. Scopolamine butylbromide (SB) and octreotide (OCT) have been successfully used with the aim of reducing gastrointestinal (GI) secretions to avoid placement of a nasogastric tube (NGT); however, there have been no comparative studies concerning the efficacy of these drugs. Furthermore, there is little information about the role played by parenteral hydration in symptom control of these patients. In a prospective trial that involved all 17 inoperable bowel-obstructed patients presenting to our services with a decompressive NGT, patients were randomized to OCT 0.3 mg/day or SB 60 mg/day for 3 days through a …

Gastrointestinal agentPalliative carebusiness.industryNauseaOctreotideAbdominal distensionmedicine.diseaselaw.inventionBowel obstructionAnesthesiology and Pain MedicineRandomized controlled triallawAnesthesiaMedicineNeurology (clinical)medicine.symptombusinessProspective cohort studyGeneral Nursingmedicine.drugJournal of Pain and Symptom Management
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Role of octreotide, scopolamine butylbromide, and hydration in symptom control of patients with inoperable bowel obstruction and nasogastric tubes: A…

2000

Bowel obstruction may be an inoperable complication in patients with end-stage cancer. Scopolamine butylbromide (SB) and octreotide (OCT) have been successfully used with the aim of reducing gastrointestinal (GI) secretions to avoid placement of a nasogastric tube (NGT); however, there have been no comparative studies concerning the efficacy of these drugs. Furthermore, there is little information about the role played by parenteral hydration in symptom control of these patients. In a prospective trial that involved all 17 inoperable bowel-obstructed patients presenting to our services with a decompressive NGT, patients were randomized to OCT 0.3 mg/day or SB 60 mg/day for 3 days through a …

Anesthesiology and Pain MedicineScopolamine butylbromideHydrationNeurology (clinical)OctreotideNursing (all)2901 Nursing (miscellaneous)Bowel obstructionCancer
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