0000000000288041
AUTHOR
W Müller-forell
Randomized trial of intravenous immunoglobulins versus prednisolone in Graves' ophthalmopathy.
Abstract Glucocorticoids are usually given for management of Graves' ophthalmopathy (GO), but they may cause side effects. By comparison, intravenous administration of immunoglobulins resulted in clinical improvement and decreased antibody titres in a large number of autoimmune diseases. Therefore, a randomized trial was done, in which 19 patients with active GO were treated with a 20-week course of oral prednisolone (P, starting dose 100 mg/day), and 21 received 1 g immunoglobulin/kg body weight for 2 consecutive days every 3 weeks. The immunoglobulin course was repeated six times. Before and at the end (20 weeks) of immunomodulating therapy, ophthalmological investigation and quantitative…
MR IMAGING AND HORMONAL FINDINGS IN PATIENTS WITH IDIOPATHIC GROWTH HORMONU DEFICIENCY
Until the introduction of MR imaging in neuroradiological diagnostic, diagnosis of the ecotopic posterior pituitary lobe, first described by the pathologist Priesel in 1920, was rare. Recently it has increasingly been diagnosed by MR in patients whose anamnesis showed birth trauma. We performed MR of the hypothalamic-pituitary region in 17 patients with idiopathic growth hormone deficiency. 8 patients had additional deficiencies of the anterior pituitary lobe whereas the function of the posterior lobe of the hypophysis was normal in all patients. Indications of birth trauma were present in only 2 patients. The cause of anterior lobe insufficiency was determined by MR in 8 patients with panh…
Neurinoma of the jugular foramen.
The complementary predications of modern imaging techniques, CT, MRI and intraarterial digital subtraction angiography (i.a. DSA), in the differential diagnosis of a neurinoma of the jugular foramen are described.