0000000000288917

AUTHOR

Eric M. Guantai

0000-0002-6440-7876

showing 8 related works from this author

Crystal Structures and Cytotoxicity of ent-Kaurane-Type Diterpenoids from Two Aspilia Species

2018

A phytochemical investigation of the roots of Aspilia pluriseta led to the isolation of ent-kaurane-type diterpenoids and additional phytochemicals (1⁻23). The structures of the isolated compounds were elucidated based on Nuclear Magnetic Resonance (NMR) spectroscopic and mass spectrometric analyses. The absolute configurations of seven of the ent-kaurane-type diterpenoids (3⁻6, 6b, 7 and 8) were determined by single crystal X-ray diffraction studies. Eleven of the compounds were also isolated from the roots and the aerial parts of Aspilia mossambicensis. The literature NMR assignments for compounds 1 and 5 were revised. In a cytotoxicity assay, 12α-methoxy-ent-kaur-9(11),1…

Lung Neoplasms<i>Aspilia mossambicensis</i>Pharmaceutical ScienceCrystal structureAspilia plurisetaAsteraceaePlant Roots01 natural sciencesAnalytical Chemistryent-kaurane diterpenoid.Drug DiscoveryAspilia mossambicensisCytotoxicityEnt kauraneta116Organisk kemiMolecular StructurebiologyChemistryLiver NeoplasmsHep G2 CellsMass spectrometricterpeenitPhytochemicalChemistry (miscellaneous)solunsalpaajatMolecular MedicinecytotoxicityasterikasvitDiterpenes KauraneAspilia<i>ent</i>-kaurane diterpenoidCarcinoma HepatocellularCell SurvivalStereochemistry010402 general chemistryta3111Articlelcsh:QD241-441lcsh:Organic chemistryHumans<i>Aspilia pluriseta</i>Physical and Theoretical ChemistryIC50x-ray crystallography010405 organic chemistrycytostatic drugsOrganic Chemistryta1182Adenocarcinoma Bronchiolo-AlveolarPlant Components AerialAsteraceaebiology.organism_classificationluonnonaineetX-ray crystal structurenaturally occurring substances0104 chemical sciencesA549 Cellsent-kaurane diterpenoidröntgenkristallografiaterpenesMolecules
researchProduct

CCDC 1868319: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographymethyl 9-hydroxy-15-[(2-methylbut-2-enoyl)oxy]kaur-16-en-18-oateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1868324: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameterskaur-9(11)-en-18-oic acidExperimental 3D Coordinates
researchProduct

CCDC 1868322: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal Systemkauran-18-oic acidCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1868321: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters15-[(2-methylbut-2-enoyl)oxy]-1617-epoxykauran-18-oic acidExperimental 3D Coordinates
researchProduct

CCDC 1868320: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters411b-dimethyl-8-methylene-12344a567891011b-dodecahydro-6a9-methanocyclohepta[a]naphthalene-4-carboxylic acidExperimental 3D Coordinates
researchProduct

CCDC 1868318: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal SystemCrystal Structure9-hydroxy-15-[(2-methylbut-2-enoyl)oxy]kaur-16-en-18-oic acidCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1868323: Experimental Crystal Structure Determination

2020

Related Article: Souaibou Yaouba, Arto Valkonen, Paolo Coghi, Jiaying Gao, Eric M. Guantai, Solomon Derese, Vincent K. W. Wong, Máté Erdélyi, Abiy Yenesew|2018|Molecules|23|3199|doi:10.3390/molecules23123199

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters15-[(2-methylbut-2-enoyl)oxy]kaur-16-en-18-oic acidExperimental 3D Coordinates
researchProduct