0000000000289271

AUTHOR

Patric Jacobs

Microfocus X-ray computed tomography analysis of corroded glass objects

Abstract Microfocus X-ray computed tomography (µCT) is a useful tool for non-destructive analysis of corroded archaeological glass objects and for monitoring restoration and conservation processes for these materials. This was demonstrated by µCT analysis of artificially corroded laboratory-produced glasses and corroded archaeological glasses retrieved from soil environments. Corrosion layers with a thickness of 20 µm or more can be detected as areas with lower X-ray attenuation values than the non-corroded glass. Features that are revealed by µCT analyses include the degree and patterns of corrosion and the presence of various internal structures in the corrosion layers. The study of resto…

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Porous Gelatin Hydrogels:  2. In Vitro Cell Interaction Study

We report on the feasibility of applying porous gelatin hydrogels, prepared by a novel and controlled cryogenic treatment, as cell-interactive scaffolds for tissue engineering applications. Despite the large number of publications on gelatin as a biomaterial, a detailed study of screening a limited number of gelatin scaffolds for their interaction with a panel of human cells has, to the best of our knowledge, not yet been published. In the present work, we have evaluated two types of porous gelatin scaffolds that differ in their pore geometry and pore size. Type I hydrogels contained top-to-bottom transverse channels (i.e. cones) with a decreasing diameter from the top (330 microm) to the b…

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Results from burial experiments with simulated medieval glasses

ABSTRACTDuring several hundred years of burial in the soil, glasses, especially those with medieval compositions, develop heavily corroded surfaces, showing phenomena such as local pitting, laminated layers and browning effects. For this study the damage phenomena have been characterised for three original glasses, using conventional methods (light microscopy and SEM of the surface and cross sections) and microfocus X-ray computed tomography (mCT), a new non-destructive analytical technique.The degradation of glass in the soil depends on a variety of parameters, concerned with the glass itself and with the burial environment. Since synergetic effects may complicate any mechanistic studies, …

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Porous gelatin cryogels as cell delivery tool in tissue engineering.

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