Plasma variations in stress markers: clinical trial of two anesthetics used in regional block in the extraction of impacted inferior third molars

Objectives: Was to evaluate the effect of different regional anesthetics (articaine with epinephrine versus prilo - caine with felypressin) on stress in the extraction of impacted lower third molars in healthy subjects. Sutdy Desing: A prospective single-blind, split-mouth cross-over randomized study was designed, with a control group. The experimental group consisted of 24 otherwise healthy male volunteers, with two impacted lower third molars which were surgically extracted after inferior alveolar nerve block (regional anesthesia), with a fortnight's interval: the right using 4% articaine with 1:100.000 epinephrine, and the left 3% prilocaine with 1:1.850.000 fely - pressin. Patients were…