0000000000291491

AUTHOR

Susanne N. Weber

showing 3 related works from this author

Baseline patient characteristics of the German multicentric prospective real-world NAFLD cohort: The Fatty Liver Assessment in Germany (FLAG) study

2019

medicine.medical_specialtybusiness.industryFatty liverPatient characteristicsmedicine.diseaselanguage.human_languageGermanInternal medicineCohortlanguagemedicineFLAG (chemotherapy)Baseline (configuration management)business35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber
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Could inherited predisposition drive fatty liver disease in non-obese Germans? Results from eight tertiary referral centers

2018

medicine.medical_specialtyReferralNon obesebusiness.industryInternal medicineFatty liverGastroenterologyMedicineDiseasebusinessmedicine.diseaseInherited PredispositionZeitschrift für Gastroenterologie
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Risk of chemotherapy-associated liver injury (CALI) in PNPLA3 p.148M allele carriers: Preliminary results of a transient elastography-based study

2019

Liver steatosis is one of the side effects of chemotherapy. The PNPLA3 p.I148M, TM6SF2 p.E167K and MBOAT7 p.G17E variants represent genetic determinants for progressive liver diseases. Here, we investigate their association with chemotherapy-associated steatosis.Prospectively, we recruited 87 patients undergoing systemic chemotherapy for gastrointestinal cancers. Hepatic fat (controlled attenuation parameter, CAP) and liver stiffness (LSM) were measured non-invasively before the initiation of chemotherapy (T0) and after at least two (T1) and four cycles (T2). Genetic variants were genotyped using allelic discrimination assays.In the final dataset (n = 60) patients demonstrated the following…

MaleHeterozygotemedicine.medical_specialtymedicine.medical_treatmentAntineoplastic AgentsGastroenterology03 medical and health sciences0302 clinical medicineFat accumulationInternal medicinemedicineHumansGenetic Predisposition to DiseaseAdiponutrinProspective StudiesAlleleeducationAllelesTriglyceridesAgedLiver injuryChemotherapyeducation.field_of_studyPolymorphism GeneticHepatologybusiness.industryGastroenterologyMembrane ProteinsLipaseMiddle Agedmedicine.diseaseFatty LiverLiver030220 oncology & carcinogenesisElasticity Imaging TechniquesFemale030211 gastroenterology & hepatologySteatosisTransient elastographybusinessAcyltransferasesTM6SF2Digestive and Liver Disease
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