0000000000293623

AUTHOR

Chao Zhao

0000-0003-1096-632x

showing 3 related works from this author

Comprehensive Overview on Multiple Strategies Fighting COVID-19

2020

Lately, myriad of novel viruses have emerged causing epidemics such as SARS, MERS, and SARS-CoV-2, leading to high mortality rates worldwide. Thus, these viruses represented a challenging threat to mankind, especially considering the miniscule data available at our disposal regarding these novel viruses. The entire world established coordinative relations in research projects regarding drug and vaccine development on the external range, whereas on the internal range, all countries declared it an emergency case through imposing different restrictions related to their border control, large gatherings, school attendance, and most social activities. Pandemic combating plans prioritized all sect…

Economic growthCoronavirus disease 2019 (COVID-19)Isolation (health care)Health Toxicology and Mutagenesismedia_common.quotation_subjectSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia Viralglobal health responseslcsh:MedicineDisaster PlanningReview010501 environmental sciencesGlobal Health01 natural sciencesRecessionBetacoronavirus03 medical and health sciences0302 clinical medicinePandemicGlobal healthHumansSocial consciousness030212 general & internal medicinePandemics0105 earth and related environmental sciencesmedia_commonSARS-CoV-2Social distancelcsh:RPublic Health Environmental and Occupational HealthCOVID-19health care systemsstrategiesCommunicable Disease ControlsymptomsBusinessCoronavirus Infectionseconomic recessionInternational Journal of Environmental Research and Public Health
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Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pande…

2020

Background Starting December 2019, mankind faced an unprecedented enemy, the COVID-19 virus. The world convened in international efforts, experiences and technologies in order to fight the emerging pandemic. Isolation, hygiene measure, diagnosis, and treatment are the most efficient ways of prevention and intervention nowadays. The health organizations and global care systems screened the available resources and offered recommendations of approved and proposed medications. However, the search for a specific selective therapy or vaccine against COVID-19 remains a challenge. Methods A literature search was performed for the screening of natural and derived bio-active compounds which showed po…

COVID-19 VaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Drug Evaluation PreclinicalPharmaceutical ScienceAntiviral AgentsArticle03 medical and health scienceschemistry.chemical_compoundClinical trials0302 clinical medicineTocilizumabChloroquineDrug DiscoveryPandemicmedicineHumansAntiviralPandemics030304 developmental biologyPharmacologyBiological ProductsClinical Trials as TopicNatural products0303 health sciencesProtectionMolecular StructureTraditional medicineSARS-CoV-2business.industryCOVID-19LycorineFingolimodCOVID-19 Drug TreatmentClinical trialConessineComplementary and alternative medicinechemistry030220 oncology & carcinogenesisMolecular MedicinePatentPlant Preparationsbusinessmedicine.drugPhytomedicine
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Dietary polyphenols as antidiabetic agents: Advances and opportunities

2020

Abstract Dietary polyphenols have been widely investigated as antidiabetic agents in cell, animals, human study, and clinical trial. The number of publication (Indexed by Web of Science) on “polyphenols and diabetes” significantly increased since 2010. This review highlights the advances and opportunities of dietary polyphenols as antidiabetic agents. Dietary polyphenols prevent and manage Type 2 diabetes mellitus via the insulin‐dependent approaches, for instance, protection of pancreatic islet β‐cell, reduction of β‐cell apoptosis, promotion of β‐cell proliferation, attenuation of oxidative stress, activation of insulin signaling, and stimulation of pancreas to secrete insulin, as well as…

bioavailability clinical study diabetes diabetic complication dietary polyphenols glucose absorption intestinal microbiota pancreatic islet -celldiabetesNutrition. Foods and food supplybusiness.industrydietary polyphenolsfood and beveragesdiabetic complicationclinical studyTP368-456Pharmacologymedicine.diseaseFood processing and manufactureGlucose absorptionBioavailabilityClinical studyglucose absorptionDiabetic complicationPolyphenolDiabetes mellitusmedicineTX341-641bioavailabilitybusinessAntidiabetic agentsFood Frontiers
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