0000000000297608

AUTHOR

Hiroshi Tanaka

showing 2 related works from this author

Hub-Centered Gene Network Reconstruction Using Automatic Relevance Determination

2012

Network inference deals with the reconstruction of biological networks from experimental data. A variety of different reverse engineering techniques are available; they differ in the underlying assumptions and mathematical models used. One common problem for all approaches stems from the complexity of the task, due to the combinatorial explosion of different network topologies for increasing network size. To handle this problem, constraints are frequently used, for example on the node degree, number of edges, or constraints on regulation functions between network components. We propose to exploit topological considerations in the inference of gene regulatory networks. Such systems are often…

Dynamic network analysisTranscription GeneticMicroarraysSciencePosterior probabilityGene regulatory networkBiologycomputer.software_genreBioinformaticsNetwork topology03 medical and health sciences0302 clinical medicineYeastsGeneticsComputer SimulationGene Regulatory NetworksGene NetworksBiology030304 developmental biologyRegulatory NetworksHyperparameter0303 health sciencesMultidisciplinaryModels GeneticSystems BiologyQuantitative Biology::Molecular NetworksCell CycleQRComputational BiologyBayesian networkGene Expression RegulationROC CurveMedicineData miningcomputerAlgorithms030217 neurology & neurosurgeryCombinatorial explosionBiological networkResearch ArticlePLoS ONE
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Coordination nano-space as stage of hydrogen ortho–para conversion

2015

The ability to design and control properties of nano-sized space in porous coordination polymers (PCPs) would provide us with an ideal stage for fascinating physical and chemical phenomena. We found an interconversion of nuclear-spin isomers for hydrogen molecule H 2 adsorbed in a Hofmann-type PCP, {Fe(pz)[Pd(CN) 4 ]} (pz=pyrazine), by the temperature dependence of Raman spectra. The ortho (o)–para (p) conversion process of H 2 is forbidden for an isolated molecule. The charge density study using synchrotron radiation X-ray diffraction reveals the electric field generated in coordination nano-space. The present results corroborate similar findings observed on different systems and confirm …

196Materials scienceHydrogenPyrazine1002chemistry.chemical_elementCatalysissymbols.namesakechemistry.chemical_compoundhydrogen storage porous coordination polymerElectric fieldNano-Moleculelcsh:ScienceMultidisciplinaryCharge density39hydrogen storage porous coordination polymer; structure of absorbed H-2; ortho-para conversion56ChemistrychemistrysymbolsPhysical chemistrylcsh:Qstructure of absorbed H2ortho–para conversionRaman spectroscopyResearch ArticleRoyal Society Open Science
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