OLIVE OIL CONSUMPTION AND RISK OF CORONARY HEART DISEASE AND/OR STROKE: A META-ANALYSIS OF CASE-CONTROL, COHORT AND INTERVENTION STUDIES

2014

Increasing evidence suggests that the Mediterranean diet can reduce the risk of CVD. Olive oil is the hallmark of this dietary pattern. We conducted a meta-analysis of case–control, prospective cohort studies and a randomised controlled trial investigating the specific association between olive oil consumption and the risk of CHD (101 460 participants) or stroke (38 673 participants). The results of all observational studies were adjusted for total energy intake. The random-effects model assessing CHD as an outcome showed a relative risk (RR) of 0·73 (95% CI 0·44, 1·21) in case–control studies and 0·96 (95% CI 0·78, 1·18) in cohort studies for a 25 g increase in olive oil consumption. In co…