0000000000302923

AUTHOR

Janusz Kasperczyk

0000-0002-8943-9508

showing 3 related works from this author

Electron-transfer reduction of selected alcohols with alkalide K−, K+(15-crown-5)2 via organometallic intermediates

2004

Abstract The course of the reaction of alkalide K − , K + (15-crown-5) 2 1 with selected alcohols depends on the kind of alcohol and the mode of substrate delivery. In the case of methanol, potassium methoxide formed initially undergoes destruction at the excess of 1 . It results in potassium oxide and methylpotassium. The latter opens the crown ether ring giving potassium tetraethylene glycoxide vinyl ether and methane. A similar course of the process is observed for propanol. Potassium glycidoxide is the main product formed in the reaction of 1 with glycidol. Its oxirane ring is opened at the excess of 1 . Organopotassium alkoxides, i.e., potassium potassiomethoxide and dipotassium potass…

chemistry.chemical_classificationPotassium methoxideAlkalidePotassiumOrganic Chemistrychemistry.chemical_elementVinyl etherBiochemistryPotassium oxideInorganic Chemistrychemistry.chemical_compoundchemistry15-Crown-5Polymer chemistryMaterials ChemistrymedicineOrganic chemistryMethanolPhysical and Theoretical ChemistryCrown ethermedicine.drugJournal of Organometallic Chemistry
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SARS-CoV-2 Antibody Screening in Healthcare Workers in Non-Infectious Hospitals in Two Different Regions of Southern Poland (Upper Silesia and Opole …

2021

(1) Background: Detection of asymptomatic or subclinical human coronavirus SARS-CoV-2 infection in healthcare workers (HCWs) is crucial for understanding the overall prevalence of the new coronavirus and its infection potential in public (non-infectious) healthcare units with emergency wards. (2) Methods: We evaluated the host serologic responses, measured with semi-quantitative ELISA tests (IgA, IgG, IgM abs) in sera of 90 individuals in Hospital no. 4 in Bytom, 84 HCWs in the University Hospital in Opole and 25 in a Miasteczko Śląskie local surgery. All volunteers had negative RT-PCR test results or had not had the RT-PCR test performed within 30 days before sampling. The ELISA test was m…

SARS-CoV-2; COVID-19; RT-PCR; asymptomatic; health-care professionals; serological surveillance; antibody screening; immunoglobulinsmedicine.medical_specialtyHealth PersonnelHealth Toxicology and MutagenesisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)serological surveillanceimmunoglobulinsRT-PCRAsymptomaticArticleantibody screeningSerology03 medical and health sciences0302 clinical medicineInternal medicineHealth caremedicineHumansasymptomaticProspective Studies030212 general & internal medicineProspective cohort study030304 developmental biologySubclinical infection0303 health scienceshealth-care professionalsbusiness.industrySARS-CoV-2Public Health Environmental and Occupational HealthRCOVID-19virus diseasesMedicinePolandmedicine.symptombusinessNon infectiousAntibody screeningInternational Journal of Environmental Research and Public Health; Volume 18; Issue 8; Pages: 4376
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Immunogenicity of the BNT162b2 mRNA COVID-19 vaccine in older residents of a long-term care facility: relation with age, frailty and prior infection …

2021

Clinical and biological assessment of the COVID-19 vaccine efficacy in the frail population is of crucial importance. The study focuses on measuring the levels of anti-SARS-CoV-2 IgG antibodies before and after BNT162b2 mRNA COVID-19 vaccination among long-term care facility (LTCF) elderly residents. We conducted a prospective, single-center, observational study among LTCF residents. The study protocol was based on three blood sample acquisitions: first taken at baseline—5 days before the first dose of the vaccine, second—20 days after the first dose, and third—12 days after the second shot of the vaccine. The comparison was made for two cohorts: patients with and without prior COVID-19 inf…

MaleAgingFrailtySARS-CoV-2COVID-19COVID-19 vaccinesLong-term careImmunogenicity VaccineOlder adultsHumansFemaleProspective StudiesRNA MessengerGeriatrics and GerontologyGerontologyBNT162 VaccineResearch ArticleAgedBiogerontology
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