0000000000304904

AUTHOR

Cam-can

showing 2 related works from this author

Physical activity predicts population-level age-related differences in frontal white matter

2018

AbstractPhysical activity has positive effects on brain health and cognitive function throughout the lifespan. Thus far, few studies have examined the effects of physical activity on white matter (WM) microstructure and psychomotor speed within the same, population-based sample (critical if conclusions are to extend to the wider population). Here, using diffusion tensor imaging and a simple reaction time task within a relatively large population-derived sample (N = 399; 18–87 years) from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), we demonstrate that physical activity mediates the effect of age on white matter integrity, measured with fractional anisotropy. Higher self-repor…

medicine.medical_specialtyeducation.field_of_studyInternal capsuleExternal capsulebusiness.industryPopulationUncinate fasciculusAudiologyCorpus callosumWhite mattermedicine.anatomical_structureFractional anisotropymedicineeducationbusinessDiffusion MRI
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Physical Activity Predicts Population-Level Age-Related Differences in Frontal White Matter

2020

Physical activity has positive effects on brain health and cognitive function throughout the life span. Thus far, few studies have examined the effects of physical activity on white matter microstructure and psychomotor speed within the same, population-based sample (critical if conclusions are to extend to the wider population). Here, using diffusion tensor imaging and a simple reaction time task within a relatively large population-derived sample (N = 399; 18–87 years) from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN), we demonstrate that physical activity mediates the effect of age on white matter integrity, measured with fractional anisotropy. Higher self-reported daily ph…

AdultMaleAgingAdolescentCognitive declineCognitionSurveys and QuestionnairesImage Processing Computer-AssistedReaction TimeHumansExerciseAgedAged 80 and overexerciseAge FactorsMiddle Agedcognitive declineWhite MatterFrontal LobeDiffusion Magnetic Resonance ImagingikääntyminenBrain agingEnglandAnisotropyFemalebrain agingaivotPsychomotor Performancefyysinen aktiivisuus
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