0000000000307010

AUTHOR

Houman Kholafazad Kordasht

Biosensing of microcystins in water samples; recent advances

Safety and quality of water are significant matters for agriculture, animals and human health. Microcystins, as secondary metabolite of cyanobacteria (blue-green algae) and cyclic heptapeptide cyanotoxin, are one of the main marine toxins in continental aquatic ecosystems. More than 100 microcystins have been identified, of which MC-LR is the most important type due to its high toxicity and common detection in the environment. Climate change is an impressive factor with effects on cyanobacterial blooms as source of microcystins. The presence of this cyanotoxin in freshwater, drinking water, water reservoir supplies and food (vegetable, fish and shellfish) has created a common phenomenon in …

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Recent advances of electrochemical and optical biosensors for detection of C-reactive protein as a major inflammatory biomarker

Abstract Early detection of inflammatory mediators including C-reactive protein (CRP) is of great diagnostic importance in many human diseases. CRP elevates very fast in conditions such as tissue injuries, infections, cancers, and renal and cardiovascular diseases. Conventional techniques for detecting CRP are based on antigen–antibody, agglutination, and precipitation reactions. Newer methods based on immunoturbidimetry and immunonephelometry are also time-consuming and relatively expensive. For solving these problems, highly efficient techniques based on CRP-biosensors have been introduced. Here, our aim was to summarize the features of recent biosensors for detection of CRP in biological…

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