0000000000310262

AUTHOR

Alessandro Malagoli

showing 4 related works from this author

Sacubitril/valsartan reduces indications for arrhythmic primary prevention in heart failure with reduced ejection fraction: insights from DISCOVER-AR…

2021

Abstract Aims This sub-study deriving from a multicentre Italian register [Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry (DISCOVER)-ARNI] investigated whether sacubitril/valsartan in addition to optimal medical therapy (OMT) could reduce the rate of implantable cardioverter-defibrillator (ICD) indications for primary prevention in heart failure with reduced ejection fraction (HFrEF) according to European guidelines indications, and its potential predictors. Methods and results In this observational study, consecutive patients with HFrEF eligible for sacubitril/valsartan from 13 Italian centres were included. Lack o…

Left ventricular strainHeart failure; Implantable cardioverter-defibrillator; Left ventricular strain; Remodelling; Sacubitril/valsartanRemodellingHeart failureSacubitril/valsartanHeart failure Implantable cardioverter-defibrillator Left ventricular strain Remodelling Sacubitril/valsartanImplantable cardioverter-defibrillator
researchProduct

Echocardiographic assessment of coronary microvascular dysfunction: Basic concepts, technical aspects, and clinical settings

2021

Abstract Coronary flow reserve is the capacity of the coronary circulation to augment the blood flow in response an increase in myocardial metabolic demands and has a powerful prognostic significance in different clinical situations. It might assess with invasive and noninvasive technique. Transthoracic echocardiography Doppler is an emerging diagnostic technique, noninvasive, highly feasible, safe for patient and physician, without radiation, and able to detect macrovascular and microvascular anomalies in the coronary circulation. This review aims to describe the benefit and limits of echocardiographic assessment of coronary flow reserve.

medicine.medical_specialtyMyocardial ischemiacoronary flow reservecoronary physiologyMyocardial IschemiaReviewsClinical settingsReview030204 cardiovascular system & hematologyDoppler echocardiographycoronary flow reserve; coronary microvascular dysfunction; coronary physiology; Doppler echocardiography; microcirculation; Blood Flow Velocity; Coronary Circulation; Echocardiography; Echocardiography Doppler; Humans; Microcirculation; Coronary Vessels; Myocardial IschemiaMicrocirculation03 medical and health sciencesCoronary circulation0302 clinical medicineCoronary CirculationInternal medicineHumansMedicineRadiology Nuclear Medicine and imaging030212 general & internal medicineCoronary Vesselcoronary microvascular dysfunctionmedicine.diagnostic_testbusiness.industryMicrocirculationDopplerCoronary flow reserveBlood flowCoronary VesselsDoppler echocardiographyEchocardiography Dopplermedicine.anatomical_structureEchocardiographyCardiologyCardiology and Cardiovascular MedicinebusinessCoronary physiologyBlood Flow VelocityHumanEchocardiography
researchProduct

Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry

2022

Aims: Sacubitril/valsartan has changed the treatment of heart failure with reduced ejection fraction (HFrEF), due to the positive effects on morbidity and mortality, partly mediated by left ventricular (LV) reverse remodelling (LVRR). The aim of this multicenter study was to identify echocardiographic predictors of LVRR after sacubitril/valsartan administration. Methods and results: Patients with HFrEF requiring therapy with sacubitril/valsartan from 13 Italian centres were included. Echocardiographic parameters including LV global longitudinal strain (GLS) and global peak atrial longitudinal strain by speckle tracking echocardiography were measured to find the predictors of LVRR [= LV end-…

EchocardiographyUltrasoundRemodellingHeart failureSacubitril/valsartanBiomarkers Cardiovascular disease Echocardiography Heart failure Imaging Remodelling Sacubitril/valsartan Speckle tracking UltrasoundCardiology and Cardiovascular MedicineCardiovascular diseaseBiomarkers; Cardiovascular disease; Echocardiography; Heart failure; Imaging; Remodelling; Sacubitril/valsartan; Speckle tracking; Ultrasound.BiomarkersImagingSpeckle tracking
researchProduct

Bicuspid aortic valve and sports: From the echocardiographic evaluation to the eligibility for sports competition

2021

Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults. Although a BAV may remain without clinical consequences for a lifetime, it can deteriorate in aortic valve stenosis and regurgitation and aortic dilatation. Unfortunately, the impact of regular training on patients with BAV and its natural course is not fully understood, although preliminary evidence suggests that the progression of valvular disease occurs primarily in an independent manner from sports practice. The current review aims to report how to perform a comprehensive echocardiographic examination in athletes with BAV and analyze the current literature on the influence of sports practice and how it imp…

Aortic valvemedicine.medical_specialtyCompetitive BehaviorEligibility DeterminationPhysical Therapy Sports Therapy and RehabilitationRegurgitation (circulation)030204 cardiovascular system & hematologyBicuspid Aortic Valve03 medical and health sciences0302 clinical medicineBicuspid aortic valveValvular diseaseBicuspid Aortic Valve DiseaseInternal medicinemedicineHumansOrthopedics and Sports MedicineEligibility DeterminationExerciseAortaAortic dilatationbiologybusiness.industryAthletes030229 sport sciencesbiology.organism_classificationmedicine.diseaseEchocardiography Dopplermedicine.anatomical_structureAortic valve stenosiscardiovascular systemCardiologybusinessDilatation PathologicPhysical Conditioning HumanSports
researchProduct