0000000000315564

AUTHOR

Blanca Sarzo

0000-0001-7305-6564

showing 4 related works from this author

Maternal Perfluoroalkyl Substances, Thyroid Hormones, and DIO Genes: A Spanish Cross-sectional Study

2021

Results of studies on perfluoroalkyl substances (PFASs) and thyroid hormones (THs) are heterogeneous, and the mechanisms underlying the action of PFASs to target THs have not been fully characterized. We examined the relation between first-trimester maternal PFAS and TH levels and the role played by polymorphisms in the iodothyronine deiodinase 1 (DIO1) and 2 (DIO2) genes in this association. Our sample comprised 919 pregnant Spanish women (recruitment = 2003-2008) with measurements of perfluorohexanesulfonic acid (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorononanoic acid (PFNA), thyroid-stimulating hormone (TSH), total triiodothyronine (TT3), and fr…

0303 health sciencesmedicine.medical_specialtyPerfluorooctanesulfonic acidTriiodothyronineCross-sectional studyDIO2General Chemistry010501 environmental sciencesBiology01 natural sciencesPerfluorononanoic acid03 medical and health scienceschemistry.chemical_compoundEndocrinologychemistryInternal medicinemedicineEnvironmental ChemistryPerfluorooctanoic acidGene030304 developmental biology0105 earth and related environmental sciencesHormoneEnvironmental Science & Technology
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Urinary Arsenic Species and Methylation Efficiency During Pregnancy: Concentrations and Associated Factors in Spanish Pregnant Women

2021

Background: Arsenic (As) is considered to be toxic for humans, the main routes of exposure being through drinking water and the diet. Once ingested, inorganic arsenic can be methylated sequentially to monomethyl and dimethyl arsenicals. Several factors can affect both As exposure and methylation efficiency. Objectives: To describe the urinary concentrations of the different As species and evaluate the methylation effi-ciency during pregnancy, as well as their associated factors in a birth cohort of pregnant Spanish women. Methods: Participants in this cross-sectional study were 1017 pregnant women from two areas of Spain who had taken part in the INMA (Environment and Childhood) project (20…

Physiologyprenatal exposureUrine010501 environmental sciences01 natural sciencesBiochemistryArsenicalschemistry.chemical_compound0302 clinical medicinecohort studies030212 general & internal medicineseleniumGeneral Environmental Scienceeducation.field_of_studyzincfood and beveragesarsenic metabolismToxicityUS populationFemalepregnancyPopulationchemistry.chemical_elementfolateMethylationseafood intake03 medical and health sciencesmedicineHumanseducationArsenic0105 earth and related environmental sciencesCreatininePregnancynational-healthbusiness.industryarsenictoxicityEnvironmental Exposurehomocysteinemedicine.diseaseone-carbon metabolismCross-Sectional StudieschemistrySpainexposurePregnant WomenArsenobetainebusinessBody mass index
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Bayesian Immature Survival Analysis of the Largest Colony of Common Murre (Uria aalge) in the Baltic Sea

2019

In long-lived species, such as seabirds, immature survival is the most important life history parameter after adult survival. The assessment of immature survival has often been difficult due to extended periods in which young birds remain unobservable at sea. This study presents results on survival of immature Common Murre (Uria aalge) obtained from an extensive mark-recapture study of a large colony at Stora Karlso in the Baltic Sea, Sweden. This colony, in contrast with other colonies, has the unique feature that many 1-year-old birds return to the colony (12%). Between 2006 and 2016, 28,930 chicks were marked at fledging, of which 5,493 individuals were later resighted in the colony. Ann…

0106 biological sciencesYounger ageBayesian probabilityFledgeZoologyBiologybiology.organism_classification010603 evolutionary biology01 natural sciences010605 ornithologyBaltic seaSurvival probabilityUria aalgeAnimal Science and ZoologyLife historySurvival analysisWaterbirds
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Prenatal arsenic exposure, arsenic methylation efficiency, and neuropsychological development among preschool children in a Spanish birth cohort.

2022

Abstract Background Prenatal arsenic (As) exposure could negatively affect child neuropsychological development, but the current evidence is inconclusive. Objectives To explore the relationship between prenatal urinary total As (TAs) concentrations, the As species and the methylation efficiency, and child neuropsychological development in a Spanish birth cohort. We also studied the effect modification produced by sex and several nutrients and elements. Materials and methods Study subjects were 807 mother–child pairs participating in the INMA (Childhood and Environment) Project. Urinary TAs and its metabolites, monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), inorganic As (iAs) and …

Urinary systemPhysiologychemistry.chemical_elementBiochemistryMethylationArsenicchemistry.chemical_compoundPregnancymedicineCacodylic AcidHumansChildArsenicGeneral Environmental SciencePregnancyCreatininebiologybusiness.industryNeuropsychologyMethylationVitaminsmedicine.diseaseFerritinchemistryChild Preschoolbiology.proteinBirth CohortFemalebusinessBirth cohortEnvironmental research
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