0000000000315669
AUTHOR
Arnold E. Kiv
Nanosensor Devices for CBRN-Agents Detection: Theory and Design
Pressing challenges of recent decades, associated with agents that are aggressive towards humans – substances and radiation of chemical, biological, radiological, and nuclear (CBRN) agents – require scientific and technological responses. These responses lie in the areas of agent detection and protection from them. The mentioned bio destructive agents can be divided into 2 groups: (1) chemical and biochemical, and (2) radiative (leading to chemical destruction of biomass). In this study, we consider models of universal track nanosensors that are capable of producing a correlated electrical response to the flow of active agents.
Improving the Design of Ion Track-Based Biosensors
In the last decade we had developed new types of biosensors, by cladding the inner walls of transparent etched swift heavy ion tracks in thin polymer foils with enzymes. The enzymatic reaction products of appropriate analytes penetrating into narrow tracks are enriched in the track’s confinement, and they change the electrical track properties if their charge states differ from those of the analytes. It was yet unknown how to design these sensors so that their best efficiency and highest possible sensitivity is achieved. This requires the accurate knowledge of the optimum track radius and the degree of product enrichment within the tracks. These questions were answered by appropriate experi…