Author: Milka Marinova

0000000000320394

AUTHOR

Milka Marinova

showing 2 related works from this author

[68Ga]Ga-DATA5m.SA.FAPi PET/CT: Specific Tracer-uptake in Focal Nodular Hyperplasia and potential Role in Liver Tumor Imaging.

2020

Computer. AutomationPET-CTPathologymedicine.medical_specialtyLiver tumorbusiness.industryLiver NeoplasmsFocal nodular hyperplasiaGallium RadioisotopesGeneral Medicinemedicine.diseaseFocal Nodular HyperplasiaPositron Emission Tomography Computed TomographyTracer uptakeMedicineHumansRadiology Nuclear Medicine and imagingbusinessNuklearmedizin. Nuclear medicine

researchProduct

Fibroblast activation protein inhibitor (FAPi) positive tumour fraction on PET/CT correlates with Ki-67 in liver metastases of neuroendocrine tumours

2021

Abstract Aim Gallium-68-labelled inhibitors of the fibroblast activation protein (FAPi) enable positron emission tomography/computed tomography (PET/CT) imaging of fibroblast activation. We evaluated if [68Ga]Ga-DATA5m.SA.FAPi PET/CT is related to Ki-67 as a marker of tumour aggressiveness in patients with liver metastases of NET. Methods Thirteen patients with liver metastases of a histologically confirmed NET who underwent PET/CT with [68Ga]Ga-DATA5m.SA.FAPi, [18F]FDG and [68Ga]Ga-DOTA-TOC were retrospectively analyzed. PET-positive liver tumour volumes were segmented for calculation of volume, SUVmax and PET-positive tumour fraction (TF). PET parameters were correlated with Ki-67. Result…

Pathologymedicine.medical_specialtyProliferation index030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineFibroblast activation protein alphaPositron Emission Tomography Computed TomographymedicineHumansRadiology Nuclear Medicine and imagingIn patientFibroblastGrading (tumors)Retrospective StudiesPET-CTbiologymedicine.diagnostic_testbusiness.industryLiver NeoplasmsGeneral MedicineFibroblastsNeuroendocrine TumorsKi-67 Antigenmedicine.anatomical_structurePositron emission tomography030220 oncology & carcinogenesisKi-67biology.proteinbusinessNuklearmedizin - NuclearMedicine

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