0000000000323256

AUTHOR

Meinhard Mende

showing 2 related works from this author

Abstract 3420: High-sensitivity Troponin T Improves Cardiovascular Risk Prediction In Patients With Cerebral Ischemia

2012

Background Patients with a cerebral ischemic event are at high risk of recurrent ischemia and other cardiovascular events. Clinical scores are recommended to predict cardiovascular risk in patients with cerebral ischemia to inform secondary preventive measures. Biomarkers may improve risk prediction beyond clinical scores and therefore secondary prevention. Methods Within the observational Find-AF trial (ISRCTN 46104198), 197 patients aged >18 years with cerebral ischemia and without atrial fibrillation had blood sampled at baseline and completed 1-year follow-up. Predictive value of 5 novel cardiovascular biomarkers for a combined vascular endpoint (acute coronary syndrome, stroke, car…

medicine.medical_specialtyAcute coronary syndromeIschemia030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineModified Rankin ScaleInternal medicineMedicineStrokeAdvanced and Specialized NursingbiologyTroponin Tbusiness.industryHazard ratioAtrial fibrillationmedicine.diseaseTroponin3. Good healthSurgerybiology.proteinCardiologyNeurology (clinical)Cardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgeryStroke
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High-sensitivity troponin assay improves prediction of cardiovascular risk in patients with cerebral ischaemia

2013

Background and purpose Clinical scores are recommended for predicting cardiovascular risk in patients with cerebral ischaemia to inform secondary prevention. Blood biomarkers may improve prediction beyond clinical scores. Methods Within the observational Find-AF trial (ISRCTN46104198), 197 patients >18 years of age with cerebral ischaemia and without atrial fibrillation had blood sampled at baseline. The predictive value of five biomarkers for a combined vascular endpoint (acute coronary syndrome, stroke, cardiovascular death) and all-cause mortality was determined, alone and in addition to the Essen Stroke Risk Score (ESRS), Stroke Prognostic Instrument 2 (SPI-2) and National Institutes of…

MaleKaplan-Meier Estimate030204 cardiovascular system & hematologyBrain IschemiaCohort Studies0302 clinical medicineNatriuretic Peptide BrainMedicine1506Prospective StudiesProspective cohort studyStrokeTroponin TAtrial fibrillationMiddle AgedPrognosisTroponin3. Good healthStrokePsychiatry and Mental healthCardiovascular DiseasesIschemic Attack TransientPredictive value of testsCardiologyFemaleFatty Acid Binding Protein 3Atrial Natriuretic Factormedicine.medical_specialtyAcute coronary syndromeGrowth Differentiation Factor 15Endpoint DeterminationCardiologyFatty Acid-Binding ProteinsRisk Assessment03 medical and health sciencesTroponin TPredictive Value of TestsInternal medicineHumansSurvival analysisAgedbusiness.industryProportional hazards modelmedicine.diseaseSurvival AnalysisPeptide FragmentsSurgeryCerebrovascular DiseaseSurgeryNeurology (clinical)businessBiomarkers030217 neurology & neurosurgeryFollow-Up StudiesJournal of Neurology, Neurosurgery & Psychiatry
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