0000000000323839
AUTHOR
M. Viola
Bovine seminal ribonuclease is cytotoxic for both malignant and normal telomerase-positive cells
Bovine seminal-ribonuclease (BS-RNase) is a member of the 'ribonucleases with special biological actions' family since it possesses specific anti-tumour, anti-spermatogenic and embryotoxic activities and exerts an immunosuppressive effect on T lymphocytes. In previous studies it was demonstrated that BS-RNase induced apoptosis in proliferating, malignant and normal cells and that telomerase activity loss also caused apoptotic death in neoplastic cells. Since an obvious relationship between cell proliferation and telomerase activity exists, the aim of this work was to study if the pro-apoptotic cytotoxic action exerted by BS-RNase on proliferating malignant cells (HT29) and proliferating nor…
Bambini pronti, insegnanti attenti
Il contributo si occupa della verifica della capacità di apprendere a leggere e a scrivere in bambini di scuola dell'infanzia; sono precisate le aree di competenza e definite le abilità prerequisite. Sono state costruite e somministrate in una sezione di scuola dell'infanzia un gruppo di prove per la rilevazione della reading readiness.