0000000000324235

AUTHOR

Wojciech Roczniak

0000-0002-6694-9425

showing 4 related works from this author

Nutritional Status and Selected Adipokines in Children with Irritable Bowel Syndrome

2022

Background: The aim of this study was to assess the nutritional status and serum concentrations of adipokines in children with irritable bowel syndrome (IBS) and healthy controls. We also sought to evaluate their relation to metabolic parameters. Methods: We studied 33 IBS patients (11 girls, 22 boys) aged 5–17 years and 30 healthy age-matched controls (11 girls, 19 boys). The analysis included anthropometric measurements, body composition parameter measurements using bioimpedance, and biochemical tests and measurements of serum concentrations of leptin, adiponectin, chemerin, and omentin-1. Results: The results of the anthropometric measurements were comparable between the patients and the…

MaleLeptinNutrition and DieteticsAdolescentNutritional StatusIrritable Bowel SyndromeAdipokinesChild Preschoolirritable bowel syndrome; leptin; adiponectin; chemerin; omentin-1; childrenHumansCytokinesIntercellular Signaling Peptides and ProteinsFemaleAdiponectinChemokinesInsulin ResistanceChildFood ScienceNutrients
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The role of adiponectin and leptin in the treatment of ovarian cancer patients

2019

Introduction: Ovarian cancer is most frequently detected in the advanced stage. Although its pathogenesis is not fully elucidated, it is assumed that body susceptibility and hormonal disorders are responsible. The role of some cytokines as predictors in the treatment process is still investigated. The aim of the study was to determine the relationship of adiponectin and leptin with the disease severity and response to chemotherapy. Material and methods: Forty-three ovarian cancer patients were treated by systemic treatment. Patients received 5–7 cycles of chemotherapy — paclitaxel/carboplatin with or without bevacizumab. Using standard ELISA kits before and after chemotherapy, adiponectin a…

AdultLeptinmedicine.medical_specialtyPaclitaxelBevacizumabEndocrinology Diabetes and Metabolismmedicine.medical_treatmentAdipokine030209 endocrinology & metabolismGastroenterologyCarboplatin03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyBlood serumInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansAgedAged 80 and overOvarian NeoplasmsChemotherapyAdiponectinbusiness.industryLeptinMiddle Agedmedicine.diseaseCarboplatinBevacizumabTreatment OutcomechemistryFemaleAdiponectinOvarian cancerbusinessBiomarkershormones hormone substitutes and hormone antagonistsmedicine.drugEndokrynologia Polska
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Exocrine Pancreatic Function in Girls with Anorexia Nervosa

2021

Objectives: To assess pancreatic exocrine function in patients with anorexia nervosa using a breath test with 13C-labeled mixed triglycerides (MTG-BT) and to determine the relationship between the test results and selected biochemical and hormonal parameters. Material and methods: Anthropometric measurements, biochemical and hormonal parameters (serum leptin, soluble leptin receptor (sLR), acylated and desacylated ghrelin, free leptin index (FLI)), and MTG-BT were performed in a group of 31 girls with the restrictive type of AN, as well as 38 healthy girls (C). Results: The average cumulative dose of 13C-triglycerides recovered with exhaled air (%CD) was similar in both study groups, while …

Leptinmedicine.medical_specialtyAnorexia NervosaAdolescentArticleExcretionInternal medicineMedicineHumansTX341-641ChildTriglyceridesBreath testNutrition and DieteticsLeptin receptormedicine.diagnostic_testbusiness.industryCumulative doseNutrition. Foods and food supplyLeptinbreath testCarbon DioxideGhrelinPancreas ExocrineEndocrinologyBreath TestsAnorexia nervosa (differential diagnoses)exocrine pancreatic functionCase-Control StudiesReceptors LeptinGhrelinFemalebusinessFood ScienceHormoneNutrients
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Serum interleukin 15 in anorexia nervosa: Comparison to normal weight and obese girls

2019

Background: Interleukin 15 (IL-15) plays a key role in the muscle-fat interaction, reducing adipose tissue mass without changes in the lean body mass and reduction of food intake. Here we assess serum IL-15 levels in girls with anorexia nervosa (AN) relative to obese and normal weight female adolescents.Methods: Serum IL-15 concentrations were evaluated using a commercially available ELISA kit in 32 Polish girls with restrictive AN, 29 girls with obesity (O), and 21 healthy controls (C). Anthropometric measurements (weight, height, BMI) and laboratory assays (serum fasting glucose, insulin, HOMA-IR, total cholesterol, HDL, LDL, triglycerides, and C-reactive protein (CRP)) were performed.Res…

medicine.medical_specialtyAnorexia NervosaAdolescentmedicine.medical_treatmentAdipose tissueAnorexia nervosaBody Mass Index03 medical and health sciences0302 clinical medicineInsulin resistanceInternal medicinemedicineHumansInsulinObesityBiological PsychiatryInterleukin-15business.industryInsulinAnthropometrymedicine.diseaseObesity030227 psychiatryPsychiatry and Mental healthEndocrinologyLean body massFemalePolandInsulin ResistancebusinessBody mass indexThe World Journal of Biological Psychiatry
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