0000000000324402

AUTHOR

J. C. Eickhoff

showing 3 related works from this author

Fragmentation of bile duct stones: a prospective systematic in vitro evaluation of argon plasma coagulation, cryotechnology, and water-jet technology

2009

Background and study aim Choledocholithiasis is a common disease in the West. Lithotripsy by mechanical methods using baskets and by laser or electrohydraulic methods varies in effectiveness. With argon plasma coagulation (APC), high temperatures are used for devitalization and fragmentation; cryogenic techniques use the selective controlled application of freeze-thaw cycles to devitalize pathological tissue; and the dissecting water jet exploits the high pressure action of a thin laminar jet. We aimed to assess the feasibility and effectiveness of APC, cryotechnology, and the dissecting water jet as options for the fragmentation of bile duct stones. Methods In an in vitro feasibility study…

medicine.medical_specialtymedicine.medical_treatmentUrologyArgon plasma coagulationGallstonesIn Vitro TechniquesLithotripsyCryosurgeryElectrocoagulationLithotripsyElectrocoagulationPressuremedicineHumansArgonFragmentation (cell biology)Jet (fluid)Bile ductbusiness.industryGastroenterologyWaterWater jetSurgeryCholedocholithiasismedicine.anatomical_structureFragmentation rateFeasibility StudiesbusinessEndoscopy
researchProduct

A phase I/II multicentric trial of gemcitabine and epirubicin in patients with advanced pancreatic carcinoma

2006

Potential synergistic interaction between gemcitabine (GEM) and epirubicin (EPI) in pancreatic cancer have been described previously. The maximum-tolerated dose in this trial was GEM 1000 mg m(-2) and EPI 45 mg m(-2). Median time to progression was 5.1 months and median survival time 7.4 months. This combination appears well tolerated and shows promising clinical activity.

OncologyAdultMaleCancer Researchmedicine.medical_specialtyPancreatic diseaseendocrine system diseasesmedicine.drug_classmedicine.medical_treatmentpancreatic cancerAntineoplastic AgentschemotherapyAntimetaboliteDeoxycytidinechemistry.chemical_compoundHemoglobinsLeukocyte CountInternal medicinePancreatic cancerClinical StudiesmedicineHumansIn patientAgedNeoplasm StagingChemotherapyDose-Response Relationship Drugbusiness.industryPlatelet CountgemcitabineMiddle Agedmedicine.diseaseepirubicinGemcitabineSurgeryPancreatic NeoplasmsOncologychemistryDeoxycytidineFemalebusinessEpirubicinmedicine.drugBritish Journal of Cancer
researchProduct

Long-Segment Early Squamous Cell Carcinoma of the Proximal Esophagus: Curative Treatment and Long-Term Follow-Up after 5-Aminolevulinic Acid (5-ALA)-…

2006

Photodynamic therapy (PDT) is an established treatment for the ablation of dysplastic Barrett's epithelium and early esophageal carcinoma, but no data have been published on curative 5-aminolevulinic acid (5-ALA)-PDT for long-segment early esophageal cancer with infiltration of the upper sphincter. We describe successful curative treatment of an unusual early long-segment squamous cell carcinoma (uT1a,N0) of the proximal esophagus (18 - 28 cm aborally), with three sessions of 5-ALA-PDT. Endoscopic and endosonographic follow-up macroscopically showed a complete remission of the tumor, proven by biopsy showing total histological ablation. After a follow-up period of 23 months, there has been …

medicine.medical_specialtyTime FactorsEsophageal NeoplasmsBiopsymedicine.medical_treatmentPhotodynamic therapyGastroenterologyDisease-Free SurvivalEndoscopy GastrointestinalInternal medicineBiopsymedicineCarcinomaHumansEsophagusPhotosensitizing Agentsmedicine.diagnostic_testbusiness.industryGastroenterologyAminolevulinic AcidMiddle AgedEsophageal cancerAblationmedicine.diseaseEndoscopymedicine.anatomical_structurePhotochemotherapyEpidermoid carcinomaCarcinoma Squamous CellbusinessFollow-Up StudiesEndoscopy
researchProduct