0000000000326176

AUTHOR

David R. Brown

showing 2 related works from this author

Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant.

2004

Background Highly publicised outbreaks of norovirus gastroenteritis in hospitals in the UK and Ireland and cruise ships in the USA sparked speculation about whether this reported activity was unusual. Methods We analysed data collected through a collaborative research and surveillance network of viral gastroenteritis in ten European countries (England and Wales were analysed as one region). We compiled data on total number of outbreaks by month, and compared genetic sequences from the isolated viruses. Data were compared with historic data from a systematic retrospective review of surveillance systems and with a central database of viral sequences. Findings Three regions (England and Wales,…

medicine.medical_specialtyvirusesmedicine.disease_causeDisease Outbreaks03 medical and health sciencesEpidemiologyEpidemic spreadmedicineHumans030304 developmental biologyCaliciviridae InfectionsRetrospective Studies0303 health sciencesInternational network030306 microbiologybusiness.industryNorovirusGenetic variantsOutbreakGenetic VariationGeneral MedicineNew variantVirology3. Good healthGastroenteritisEuropePopulation SurveillanceMutationNorovirusFood MicrobiologyViral diseaseSeasonsbusinessLancet (London, England)
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Hemicellulose hydrolysis catalysed by solid acids

2013

Depolymerising hemicellulose into platform sugar molecules is a key step in developing the concept of an integrated biorefinery. This reaction is traditionally catalysed by either enzymes or homogeneous mineral acids. We compared various solid catalysts for hemicellulose hydrolysis, running reactions in water, under neutral pH and relatively mild temperature and pressure (120°C and 10 bar) conditions. Sulphonated resins are highly active, but they leach out sulphonic groups. Sulphonated silicas are less active, but more stable. They have weakly and strongly bound sites and the strongly bound ones do not leach. Zeolites are moderately active and stable. Among them, H-ferrierite especially, d…

chemistry.chemical_classificationChemistryBiorefineryCatalysisCatalysischemistry.chemical_compoundHydrolysisEnzymeHemicellulose heterogeneous catalysis solid acids xylose arabinose zeolitesHomogeneousOrganic chemistryMoleculeQDHemicelluloseSugar
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