0000000000328515

AUTHOR

Androniks Mitildzans

showing 2 related works from this author

Increased numbers of CD4 and CD8 positive T lymphocytes with decreased CD4/CD8 ratio in patients with high grade CIN lesions

2016

medicine.medical_specialtyDecreased CD4+/CD8+ ratioHigh-Grade CINReproductive Medicinebusiness.industryInternal medicineObstetrics and GynecologyMedicineIn patientbusinessGastroenterologyCD8European Journal of Obstetrics & Gynecology and Reproductive Biology
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Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia

2017

Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…

p530301 basic medicineUterine Cervical Neoplasmsurologic and male genital diseasesGastroenterology0302 clinical medicineYoung adultCervical cancerp63medicine.diagnostic_testbiologyvirus diseasesMiddle AgedImmunohistochemistryfemale genital diseases and pregnancy complicationsKoilocytesurgical procedures operativemedicine.anatomical_structure030220 oncology & carcinogenesisKi-67Disease ProgressionKi-67ImmunohistochemistryFemalelcsh:RB1-214Adultmedicine.medical_specialtyAdolescentCervical intraepithelial neoplasiaPathology and Forensic MedicineYoung Adult03 medical and health sciencesInternal medicineBiopsyBiomarkers Tumorlcsh:PathologymedicineHumansneoplasmsCervixCervical intraepithelial neoplasiabusiness.industryMembrane ProteinsUterine Cervical Dysplasiamedicine.diseaseKi-67 Antigen030104 developmental biologybiology.proteinTumor Suppressor Protein p53businessTurkish Journal of Pathology
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