0000000000329000
AUTHOR
Mark Golberg
Speckle based configuration for simultaneousin vitroinspection of mechanical contractions of cardiac myocyte cells
In this manuscript we propose optical lensless configuration for a remote non-contact measuring of mechanical contractions of vast number of cardiac myocytes. All the myocytes were taken from rats, and the measurements were done in an in vitro mode. The optical method is based on temporal analysis of secondary reflected speckle patterns generated in lensless microscope configuration. The processing involves analyzing the movement and the change in the statistics of the generated secondary speckle patterns that are created on top of the cell culture when it is illuminated by a spot of laser beam. The main advantage of the proposed system is the ability to measure many cells simultaneously (a…
In Depth Flow Inspection based on Spatial Analysis of Dynamic Laser Speckle
A novel optical approach based on statistical analysis of spatial laser speckle pattern for tissue in-depth flow characteristics is presented. Properties such as flow orientation and speed can be estimated. In-vitro experimental results are demonstrated.
Speckle-based configuration for simultaneous in vitro inspection of mechanical contractions of cardiac myocyte cells.
An optical lensless configuration for a remote noncontact measuring of mechanical contractions of a vast number of cardiac myocytes is proposed. All the myocytes were taken from rats, and the measurements were done in an in vitro mode. The optical method is based on temporal analysis of secondary reflected speckle patterns generated in lensless microscope configuration. The processing involves analyzing the movement and the change in the statistics of the secondary speckle patterns that are created on top of the cell culture when it is illuminated by a spot of laser beam. The main advantage of the proposed system is the ability to measure many cells simultaneously (∼1000 cells) and to extra…