0000000000330274
AUTHOR
Bersano A.
Artery occlusion independently predicts unfavorable outcome in cervical artery dissection
ObjectiveTo assess the impact of dissected artery occlusion (DAO) on functional outcome and complications in patients with cervical artery dissection (CeAD).MethodsWe analyzed combined individual patient data from 3 multicenter cohorts of consecutive patients with CeAD (the Cervical Artery Dissection and Ischemic Stroke Patients [CADISP]–Plus consortium dataset). Patients with data on DAO and functional outcome were included. We compared patients with DAO to those without DAO. Primary outcome was favorable functional outcome (i.e., modified Rankin Scale [mRS] score 0–1) measured 3–6 months from baseline. Secondary outcomes included delayed cerebral ischemia, major hemorrhage, recurrent CeAD…
Cold Leg LBLOCA uncertainty analysis using TRACE/DAKOTA coupling
Abstract Safety analyses for nuclear power plants were carried out in the past using a conservative approach. With the increase of the phenomenological knowledge, through experimental data, and computational power, it became possible to adopt best estimate thermal- hydraulic system codes to perform deterministic safety analyses. However, some uncertainties are still present in the models, correlations, initial and boundary conditions, etc. Therefore, it is fundamental to quantify the uncertainty of calculation. This approach is called “Best Estimate Plus Uncertainty” (BEPU). Among the available uncertainty analysis methodologies, the probabilistic method to propagate input uncertainty is wi…