0000000000330656

AUTHOR

Christina Gratziou

showing 3 related works from this author

Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from…

2021

Background: Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterised by chronic rhinosinusitis, nasal polyps, asthma and aspirin intolerance. An imbalance of eicosanoid metabolism with anover-production of cysteinyl leukotrienes (CysLTs) has been associated with AERD. However, the precise mechanisms underlying AERD are unknown. Objective: To establish the transcriptome of the nasal polyp airway epithelial cells derived from AERD patients to discover gene expression patterns in this disease. Methods: Nasal airway epithelial cells were isolated from 12 AERD polyps and 8 AERD non-polyp nasal mucosa samples as controls from the same subjects. Utilising the Illumina HiSeq 2500 …

0301 basic medicineMaleMucous membrane of noseBiochemistryDMRT3TranscriptomeTranscription Factors TFII0302 clinical medicinetranscriptome analysisGene expressionMedicineNasal polypsRNA-SeqEicosanoid metabolismAnti-Inflammatory Agents Non-SteroidalMiddle AgedImmunohistochemistryQR1-502030220 oncology & carcinogenesisImmunohistochemistryFemalemedicine.symptomAdultLeukotrienesAspirin-exacerbated respiratory diseaseInflammationMicrobiologyArticle03 medical and health sciencesImmune systemNasal Polypsotorhinolaryngologic diseasesHumansSinusitisMolecular BiologySkin TestsAspirinbusiness.industryGene Expression Profilingnasal airwayEpithelial Cellsmedicine.diseaseRespiration Disorders030104 developmental biologyImmunologyChronic DiseaseNasal LavageAsthma Aspirin-InducedbusinessTranscriptomeBiomolecules
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New rules on driver licensing for patients with obstructive sleep apnea: European Union Directive 2014/85/EU

2016

Editorial, no abstract

medicine.medical_specialtybusiness.industryMedicine (all)Cognitive NeuroscienceApplied psychologyAlternative medicineGeneral MedicineDriver licensingCognitive neuroscienceBehavioral neuroscienceDirectivemedicine.diseaseObstructive sleep apnea03 medical and health sciencesBehavioral Neuroscience0302 clinical medicine030228 respiratory systemMedicinemedia_common.cataloged_instanceEuropean unionbusiness030217 neurology & neurosurgerymedia_commonJournal of Sleep Research
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New rules on driver licensing for patients with obstructive sleep apnoea: EU Directive 2014/85/EU.

2016

The widespread recognition that obstructive sleep apnoea (OSA) represents an important risk factor for motor vehicle accidents (MVA), which is reversed by successful therapy with continuous positive airway pressure (CPAP), has led to a revision of annex III of the European Union (EU) directive on driving licences that is subject to mandatory implementation by all member states from December 31, 2015 [1]. This directive was the result of recommendations from a working group established by the Transport and Mobility Directorate of the European Commission in 2012 [2]. The directive states [1] Joint ERS/ESRS working group on the EU directive on issuing driving licences in obstructive sleep apno…

Pulmonary and Respiratory MedicineAutomobile Drivingmedicine.medical_treatmentsleepinessSeverity of Illness Index03 medical and health sciences0302 clinical medicinemedia_common.cataloged_instanceMedicineHumansEuropean commissionOperations managementContinuous positive airway pressureEuropean UnionEuropean unionmedia_commonLicensureSleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryMember statesAccidents TrafficDriver licensingDirectiverespiratory tract diseases030228 respiratory systemSleep (system call)businessLicensure030217 neurology & neurosurgery
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