0000000000336488
AUTHOR
A. Cuccia
showing 5 related works from this author
Effectiveness of cyclosporine A in patients with moderate to severe plaque psoriasis in a real-life clinical setting in Italy: the TRANSITION study
2020
Background: Cyclosporine A (CsA) is one of the systemic therapeutic options for moderate-to-severe psoriasis, based on its efficacy and rapidity of action. The current study investigated the response to CsA in patients with moderate-to-severe plaque psoriasis. Materials and Methods: TRANSITION was an observational, cross-sectional, multicentre study which evaluated the proportion of partial- and suboptimal-responders among patients with moderate-to-severe plaque psoriasis treated with continuous CsA for >= 12 weeks. Patients demonstrating a Psoriasis Area and Severity Index (PASI) response of >= 90, >= 75 and <90, >= 50 and <75 and <50 were defined as responders, subopt…
Search for Pulsed Gamma Ray Emission above 50 MeV from NP 0532
1971
OBSERVATIONS of the pulsar NP 0532 in the gamma ray region have yielded evidence of pulsed gamma ray emission for energies up to 10 MeV (refs. 1, 2 and Kurfess, to be published). Above this energy, upper limits between 10 MeV and 150 MeV (refs. 3, 4) and above 50 MeV (ref. 5) are indicated. A result above 70 MeV with phase error of 3 ms with respect to optical signal has been given by a counter experiment6.
Il F.S.N. della Regione Siciliana ex art. 38 Statuto per la perequazione infrastrutturale - Una ricerca empirica sulle sue potenzialità inattuate
2016
The aim of the paper is to depict the development over time of F.S.N. as item of the financial statements of Sicily that crystallizes the duty of the Italian State to fill in the infrastructural gap that Sicily has historically experienced respect to the rest of the country. This item might be seen as a provisional State subsidy since theoretically the gap should have been closed at the end and at the same time the Sicilian Region would have ended up with be more able to provide for itself. Hence, the paper aims at assessing to what extent the article no. 38 of the Statute of Sicily - as rule that has made this capital grant formally established - has been applied, by comparing how much it …
Pruritus characteristics in a large Italian cohort of psoriatic patients
2019
Background: Psoriasis (Ps) is a chronic systemic autoimmune disease associated with pruritus in 64–98% of patients. However, few modestly sized studies assess factors associated with psoriatic pruritus. Objective: To investigate factors associated with Ps pruritus intensity. Methods: Psoriasis patients 18 years or older seen in one of 155 centres in Italy between September 2005 and 2009 were identified from the Italian PsoCare registry. Patients without cutaneous psoriasis and those with missed information on pruritus were excluded. Results: We identified 10 802 patients, with a mean age 48.8 ± 14.3 years. Mild itch was present in 33.2% of patients, moderate in 34.4%, severe in 18.7% and ve…
Efficacy of switching between tumor necrosis factor-alfa inhibitors in psoriasis: results from the Italian Psocare registry
2014
Background: Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. Objective: We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discontinuing the first TNF-alfa inhibitor. Methods: Data from all 5423 consecutive patients starting TNF-alfa inhibitor therapy for psoriasis between September 2005 and September 2010 who were included in the Italian Psocare registry were analyzed. Results: In 105 patients who switched to a second TNF-alfa inhibitor who had complete follow-up data, 75% improvement in the Psoriasis …