0000000000337756

AUTHOR

Domenico Otranto

0000-0002-7518-476x

showing 4 related works from this author

Leishmania tarentolae and Leishmania infantum in humans, dogs and cats in the Pelagie archipelago, southern Italy.

2021

Visceral leishmaniasis (VL) caused by Leishmania infantum is endemic in the Mediterranean basin with most of the infected human patients remaining asymptomatic. Recently, the saurian-associated Leishmania tarentolae was detected in human blood donors and in sheltered dogs. The circulation of L. infantum and L. tarentolae was investigated in humans, dogs and cats living in the Pelagie islands (Sicily, Italy) by multiple serological and molecular testing. Human serum samples (n = 346) were tested to assess the exposure to L. infantum by immunofluorescence antibody test (IFAT), enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) and to L. tarentolae by IFAT. Meanwhile, sera from do…

dogsreal-time polymerase chain reactionRC955-962Pathology and Laboratory MedicineSerologyMedical ConditionswesternZoonosesArctic medicine. Tropical medicineitalymiddle agedMedicine and Health Sciences80 and overadult; aged; aged 80 and over; animals; blotting western; cat diseases; cats; dog diseases; dogs; enzyme-linked immunosorbent assay; female; humans; italy; leishmaniasis visceral; male; middle aged; prevalence; public health; real-time polymerase chain reaction; serologic tests; sicily; surveys and questionnaires; young adult; leishmania infantumEnzyme-Linked ImmunoassayshumansAged 80 and overProtozoansLeishmaniaMammalsCATSmedicine.diagnostic_testbiologyadultpublic healthEukaryotablottingvisceralanimalsagedInfectious DiseasesSerologyfemaleVertebratesleishmania infantumLeishmaniasis Visceralyoung adultLeishmania infantumAntibodyDog DiseasePublic aspects of medicineRA1-1270dog diseasesHumanResearch ArticleNeglected Tropical DiseasesBlotting Westernprevalenceserologic testsImmunofluorescenceResearch and Analysis MethodsmaleSurveys and Questionnaires ...parasitic diseasesmedicineParasitic DiseasessicilyImmunoassaysleishmaniasisProtozoan InfectionsAnimalcatsPublic Health Environmental and Occupational HealthOrganismsBiology and Life SciencesLeishmaniasiscat diseasesbiology.organism_classificationmedicine.diseaseLeishmaniaCat DiseaseTropical DiseasesVirologyParasitic ProtozoansVisceral leishmaniasisAmniotessurveys and questionnairesbiology.proteinImmunologic Techniquesenzyme-linked immunosorbent assayZoologyPLoS Neglected Tropical Diseases
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Zoonotic Dirofilaria immitis and Dirofilaria repens infection in humans and an integrative approach to the diagnosis

2021

Abstract Dirofilariosis by Dirofilaria immitis and Dirofilaria repens is endemic in dogs from countries of the Mediterranean basin. Both species may infect humans, with most of the infected patients remaining asymptomatic. Based on the recent description of the southernmost hyperendemic European focus of heartworm disease in dogs from the Pelagie archipelagos, we performed a serological and molecular survey in human population of that area. Human blood samples were collected in the islands of Linosa (n=101) and Lampedusa (n=296) and tested by ELISA and molecular test for the detection of D. immitis and D. repens. Samples were also screened for filarioid-associated endosymbionts, Wolbachia s…

dogsDirofilaria immitisVeterinary (miscellaneous)PopulationDirofilaria immitisDirofilariasiCanine heartworm disease; Dirofilariasis; Dogs; Humans; One Health; Vector-borne zoonosis; Animals; Dog Diseases; Dogs; Humans; Islands; Italy; Phylogeny; Seroepidemiologic Studies; Dirofilaria immitis; Dirofilaria repens; Dirofilariasis; ZoonosesRepensVector-borne zoonosis.one healthdirofilariasisSeroepidemiologic StudiesZoonosesDirofilariasisparasitic diseasesDogcanine heartworm disease; dirofilariasis; dogs; humans; one health; vector-borne zoonosismedicineAnimalsSeroprevalenceDog DiseaseshumanseducationPhylogenyDirofilariaIslandseducation.field_of_studybiologycanine heartworm diseasebiology.organism_classificationmedicine.diseaseVirologyDirofilaria repensInfectious DiseasesItalyInsect ScienceDirofilaria repensParasitologyWolbachiavector-borne zoonosisHumanActa Tropica
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Ticks infesting humans in Italy and associated pathogens

2014

Background: Ticks may transmit a large variety of pathogens, which cause illnesses in animals and humans, commonly referred to as to tick-borne diseases (TBDs). The incidence of human TBDs in Italy is underestimated because of poor surveillance and the scant amount of studies available. Methods. Samples (n = 561) were collected from humans in four main geographical areas of Italy (i.e., northwestern, northeastern, southern Italy, and Sicily), which represent a variety of environments. After being morphologically identified, ticks were molecularly tested with selected protocols for the presence of pathogens of the genera Rickettsia, Babesia, Theileria, Candidatus Neoehrlichia mikurensis, Bor…

MaleVeterinary medicineBorrelia valaisianaSettore MED/17 - Malattie InfettiveRhipicephalus sanguineusInfectious DiseaseDistributionBorrelia afzeliimedicine.disease_causeTicksparasitic diseasesmedicineTick-borne diseasesHumansAnimalsTick-borne diseasebiologyPathogenAnimalMedicine (all)ResearchTick-borne diseasebiology.organism_classificationmedicine.diseaseHaemaphysalisbacterial infections and mycosesTick InfestationTick InfestationsRhipicephalusInfectious DiseasesItalyIxodesParasitologyFemaleDistribution; Humans; Italy; Pathogens; Tick-borne diseases; Ticks; Animals; Female; Humans; Italy; Male; Tick Infestations; Ticks; Parasitology; Infectious Diseases; Medicine (all)PathogensDermacentorHumanTick
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The European wildcats (Felis silvestris silvestris) as reservoir hosts of Troglostrongylus brevior (Strongylida: Crenosomatidae) lungworms.

2014

The increasing reports of Troglostrongylus brevior lungworm in domestic cats from Italy and Spain raised questions on its factual distribution and on the role wildcats play as reservoirs of these parasites. Carcasses of 21 wildcats were collected in natural parks of southern Italy (i.e., Catania, Sicily n = 5 and Matera, Basilicata n = 16) and biometrically and genetically identified as Felis silvestris silvestris, but two as hybrids. Troglostrongylus brevior and Eucoleus aerophilus lungworms were found in 15 (71.4%) and 7 (33.3%) individuals, respectively, being five (23.8%) co-infected by the two species. Both lungworms showed an aggregated distribution in the host population, assessed by…

Lung DiseasesVeterinary medicinePopulationbiology.animal_breedEndangered speciesSettore BIO/05 - ZoologiaBiologyTroglostrongylus breviorWildcat hybridTroglostrongylus breviorFelisAnimalseducationStrongylidaEucoleus aerophiluWildcatDisease ReservoirsStrongylida InfectionsFelis silvestris silvestriseducation.field_of_studyGeneral VeterinaryFelisEucoleus aerophilusGeneral MedicineLungwormsbiology.organism_classificationItalyWildcat hybridsEuropean wildcatStrongylidaParasitologyEucoleus aerophilusLungwormFe lis silvestris silvestri
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