Search for new physics inlepton+photon+Xevents with929  pb−1ofpp¯collisions ats=1.96  TeV

The authors present results of a search for anomalous production of events containing a charged lepton ({ell}, either e or {mu}) and a photon ({gamma}), both with high transverse momentum, accompanied by additional signatures, X, including missing transverse energy (E{sub T}) and additional leptons and photons. We use the same kinematic selection criteria as in a previous CDF search, but with a substantially larger data set, 305 pb{sup -1}, a p{bar p} collision energy of 1.96 TeV, and the upgraded CDF II detector. We find 42 {ell}{gamma}E{sub T} events versus a standard model expectation of 37.3 {+-} 5.4 events. The level of excess observed in Run I, 16 events with an expectation of 7.6 {+-…

Optimizing taxane use in MBC in the emerging era of targeted chemotherapy.

The first-generation taxanes, conventional paclitaxel and docetaxel, are established treatment options for adjuvant and metastatic breast cancer (MBC). However, these agents have limitations, including primary/secondary resistance and harsh toxicities. The introduction of paclitaxel albumin represents a significant advance in taxane therapy as the first of a new generation of taxanes. This agent utilizes albumin pathways to achieve enhanced and targeted drug delivery to the tumour. The lack of solvent also means that it is well tolerated, despite the lack of premedications. Paclitaxel albumin is licensed in the United States and Europe as ≥2nd-line therapy in MBC (260mg/m(2) once every thre…

Poster: Polar Dielectrics, Optics, and Ionics

First Observation of Top Quark Production in the Forward Region

Top quark production in the forward region in proton-proton collisions is observed for the first time. The W + b final state with W → μν is reconstructed using muons with a transverse momentum, p[subscript T], larger than 25 GeV in the pseudorapidity range 2.0 20  GeV. The results are based on data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected at center-of-mass energies of 7 and 8 TeV by LHCb. The inclusive top quark production cross sections in the fiducial region are σ(top)[7  TeV] = 239 ± 53(stat) ± 33(syst) ± 24(theory)  fb, σ(top)[8  TeV] = 289 ± 43(stat) ± 40(syst) ± 29(theory)  fb.These results, along with the observed differential yields and c…

Measurement of Inclusive Jet Cross Sections inZ/γ*(→e+e−)+jetsProduction inpp¯Collisions ats=1.96   TeV

Inclusive jet cross sections in Z/{gamma}* events, with Z/{gamma}* decaying into an electron-positron pair, are measured as a function of jet transverse momentum and jet multiplicity in p{bar p} collisions at {radical}s - 1.96 TeV with the upgraded Collider Detector at Fermilab in Run II, based on an integrated luminosity of 1.7 fb{sup -1}. The measurements cover the rapidity region |y{sup jet}| 30 GeV/c. Next-to-leading order perturbative QCD predictions are in good agreement with the measured cross sections.

Study of W Boson Production in Association with Beauty and Charm

The associated production of a W boson with a jet originating from either a light parton or heavy-flavor quark is studied in the forward region using proton-proton collisions. The analysis uses data corresponding to integrated luminosities of 1.0 and 2.0  fb[superscript -1] collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV, respectively. The W bosons are reconstructed using the W → μν decay and muons with a transverse momentum, p[subscript T], larger than 20 GeV in the pseudorapidity range 2.0 20  GeV and 2.2 20  GeV. The fraction of W + jet events that originate from beauty and charm quarks is measured, along with the charge asymmetries of the W + b and W + c produ…

Strong Evidence forZZProduction inpp¯Collisions ats=1.96  TeV

We report the first measurement of the cross section for Z boson pair production at a hadron collider. This result is based on a data sample corresponding to 1.9 fb{sup -1} of integrated luminosity from p{bar p} collisions at {radical}s = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. In the {ell}{ell}{ell}{prime}{ell}{prime} channel, we observe three ZZ candidates with an expected background of 0.096{sub -0.063}{sup +0.092} events. In the {ell}{ell}{nu}{nu} channel, we use a leading-order calculation of the relative ZZ and WW event probabilities to discriminate between signal and background. In the combination of {ell}{ell}{ell}{prime}{ell}{prime} and {ell}{ell}{nu}{…

Measurement of thepp¯→tt¯production cross section and the top quark mass ats=1.96  TeVin the all-hadronic decay mode

We report the measurements of the t{bar t} production cross section and of the top quark mass using 1.02 fb{sup -1} of p{bar p} data collected with the CDF II detector at the Fermilab Tevatron. We select events with six or more jets on which a number of kinematical requirements are imposed by means of a neural network algorithm. At least one of these jets must be identified as initiated by a b-quark candidate by the reconstruction of a secondary vertex. The cross section is measured to be {sigma}{sub t{bar t}} = 8.3 {+-} 1.0(stat. ){sup +2.0}{sub -1.5}(syst.) {+-} 0.5(lumi.) pb, which is consistent with the standard model prediction. The top quark mass of 174.0 {+-} 2.2(stat.){+-}4.8(syst.)…

Measurement of CP asymmetry in Bs0 → Ds ∓K± decays

Journal of high energy physics 2018(3), 59 (2018). doi:10.1007/JHEP03(2018)059

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

Observation of Orbitally Excited Bs Mesons

We report the first observation of two narrow resonances consistent with states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+, \bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1}) = 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.

Limits on anomalous triple gauge couplings inpp¯collisions ats=1.96  TeV

We present a search for anomalous triple gauge couplings (ATGC) in WW and WZ boson production. The boson pairs are produced in p (p) over bar collisions at root s = 1.96 TeV, and the data sample corresponds to 350 pb(-1) of integrated luminosity collected with the CDF II detector at the Fermilab Tevatron. In this search one W decays to leptons, and the other boson (W or Z) decays hadronically. Combining with a previously published CDF measurement of W gamma boson production yields ATGC limits of -0.18 <lambda < 0.17 and -0.46 <Delta kappa < 0.39 at the 95% confidence level, using a cutoff scale Lambda=1.5 TeV.

Search for Maximal Flavor Violating Scalars in Same-Charge Lepton Pairs inpp¯Collisions ats=1.96  TeV

Models of maximal flavor violation (MxFV) in elementary particle physics may contain at least one new scalar SU(2) doublet field {phi}{sub FV}=({eta}{sup 0},{eta}{sup +}) that couples the first and third generation quarks (q{sub 1}, q{sub 3}) via a Lagrangian term L{sub FV}={xi}{sub 13}{phi}{sub FV}q{sub 1}q{sub 3}. These models have a distinctive signature of same-charge top-quark pairs and evade flavor-changing limits from meson mixing measurements. Data corresponding to 2 fb{sup -1} collected by the Collider Dectector at Fermilab II detector in pp collisions at {radical}(s)=1.96 TeV are analyzed for evidence of the MxFV signature. For a neutral scalar {eta}{sup 0} with m{sub {eta}{sup 0}…

Studies of the resonance structure inD0→KS0K±π∓decays

Amplitude models are constructed to describe the resonance structure of D0→ K-π+π+π- and D0→ K+π-π-π+ decays using pp collision data collected at centre-of-mass energies of 7 and 8 TeV with the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb- 1. The largest contributions to both decay amplitudes are found to come from axial resonances, with decay modes D0→ a1(1260) +K- and D0→ K1(1270 / 1400) +π- being prominent in D0→ K-π+π+π- and D0→ K+π-π-π+, respectively. Precise measurements of the lineshape parameters and couplings of the a1(1260) +, K1(1270) - and K(1460) - resonances are made, and a quasi model-independent study of the K(1460) - resonance is performed. The coher…

Search for the Higgs Boson in Events with Missing Transverse Energy andbQuark Jets Produced inpp¯Collisions ats=1.96  TeV

We search for the standard model Higgs boson produced in association with an electroweak vector boson in events with no identified charged leptons, large imbalance in transverse momentum, and two jets where at least one contains a secondary vertex consistent with the decay of b hadrons. We use {approx}1 fb{sup -1} integrated luminosity of p{bar p} collisions at {radical}s = 1.96 TeV recorded by the CDF II experiment at the Tevatron. We find 268 (16) single (double) b-tagged candidate events, where 248 {+-} 43 (14.4 {+-} 2.7) are expected from standard model background processes. We place 95% confidence level upper limits on the Higgs boson production cross section for several Higgs boson ma…

Search for weakly decaying b -flavored pentaquarks

Investigations of the existence of pentaquark states containing a single $b$ (anti)quark decaying weakly into four specific final states J/$\psi K^+\pi^- p$, J/$\psi K^- \pi^- p$, J/$\psi K^- \pi^+ p$, and $J/\psi \phi (1020) p$ are reported. The data sample corresponds to an integrated luminosity of 3.0/fb in 7 and 8 TeV pp collisions acquired with the LHCb detector. Signals are not observed and upper limits are set on the product of the production cross section times branching fraction with respect to that of the $\Lambda_b$.

Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

The outbreak of severe acute respiratory syndromecoronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide.1 It has had an unprecedented influence on cardiac surgery internationally, resulting in cautious delivery of surgery and restructuring of services.2 Understanding the influence of COVID-19 on patients after cardiac surgery is based on assumptions from other surgical specialties and single-center studies. The COVIDSurg Collaborative conducted a multicenter cohort study, including 1128 patients, across 235 hospitals, from 24 countries demonstrating perioperative COVID-19 infection…

Measurement of theΛb0Lifetime inΛb0→Λc+π−Decays inpp¯Collisions ats=1.96  TeV

We thank the Fermilab staff and the technical staffs of the participating institutions for their vital contributions. This work was supported by the U.S. Department of Energy and National Science Foundation; the Italian Istituto Nazionale di Fisica Nucleare; the Ministry of Education, Culture, Sports, Science and Technology of Japan; the Natural Sciences and Engineering Research Council of Canada; the National Science Council of the Republic of China; the Swiss National Science Foundation; the A.P. Sloan Foundation; the Bundesministerium fur Bildung und Forschung, Germany; the World Class University Program, the National Research Foundation of Korea; the Science and Technology Facilities Co…

Observation and Mass Measurement of the BaryonΞb−

We report the observation and measurement of the mass of the bottom, strange baryon $\Xi^-_b$ through the decay chain $\Xi^-_b \to J/\psi \Xi^-$, where $J/\psi \to \mu^+ \mu^-$, $\Xi^- \to \Lambda \pi^-$, and $\Lambda \to p \pi^-$. Evidence for observation is based on a signal whose probability of arising from the estimated background is 6.6 x 10^{-15}, or 7.7 Gaussian standard deviations. The $\Xi^-_b$ mass is measured to be $5792.9\pm 2.5$ (stat.) $\pm 1.7$ (syst.) MeV/$c^2$.

Search for third generation vector leptoquarks inpp¯collisions ats=1.96  TeV

We search for a third generation vector leptoquark (VLQ3) that decays to a b quark and tau lepton using the CDF II detector and 320pb-1 of integrated luminosity from the Fermilab Tevatron. Observing a number of events in agreement with standard model expectations, we obtain, assuming Yang-Mills (minimal) couplings, the most stringent upper limit on the VLQ3 pair production cross section of 344 fb (493 fb) and lower limit on the VLQ3 mass of 317GeV/c2 (251GeV/c2) at 95% C.L. © 2008 The American Physical Society.

Search for standard model Higgs bosons produced in association with W bosons.

We report on the results of a search for standard model Higgs bosons produced in association with W bosons from p-pbar collisions at root s = 1.96 TeV. The search uses a data sample corresponding to approximately 1 fb-1 of integrated luminosity. Events consistent with the W to l-nu and H to b-bbar signature are selected by triggering on a high-pT electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light flavor jets, increasing the b-jet purity in the sample and thereby reducing the background to Higgs boson production. We observe no excess l-nu-b-bbar production beyond the …

Cross section measurements of high-p(T) dilepton final-state processes using a global fitting method

We present a new method for studying high-$p_T$ dilepton events ($e^{\pm}e^{\mp}$, $\mu^{\pm}\mu^{\mp}$, $e^{\pm}\mu^{\mp}$) and simultaneously extracting the production cross sections of $p\bar{p} \to t\bar{t}$, $p\bar{p} \to W^+W^-$, and $p\bar{p} \to \ztt$ at a center-of-mass energy of $\sqrt{s} = 1.96$ TeV. We perform a likelihood fit to the dilepton data in a parameter space defined by the missing transverse energy and the number of jets in the event. Our results, which use $360 {\rm pb^{-1}}$ of data recorded with the CDF II detector at the Fermilab Tevatron Collider, are $\sigma(t\bar{t}) = 8.5_{-2.2}^{+2.7}$ pb, $\sigma(W^+W^-) = 16.3^{+5.2}_{-4.4}$ pb, and $\sigma(\ztt) =291^{+50}_…

Abstract GS2-04: Efficacy results from CIBOMA/2004-01_GEICAM/2003-11 study: A randomized phase III trial assessing adjuvant capecitabine after standard chemotherapy for patients with early triple negative breast cancer

Abstract Background: Triple negative breast cancers (TNBC) have a greater risk of relapse than non-TNBC. New therapeutic approaches are needed for these patients (pts). CIBOMA/2004-01_GEICAM/2003-11 is a multinational, randomized phase III trial exploring adjuvant capecitabine (X) after completion of standard treatment in early TNBC pts. Materials and Methods: Patients with operable, node-positive (or node-negative with tumor size ≥ 1 cm), centrally confirmed hormone receptor-negative, HER2-negative early BC, who had received 6–8 cycles (cy) of standard anthracycline and/or taxane-containing chemotherapy or 4 cy of doxorubicin-cyclophosphamide (for node-negative disease) in the (neo)adjuvan…

First measurement of the W-boson mass in run II of the Tevatron.

7 pages, 4 figures.-- PACS nrs.: 14.70.Fm; 13.38.Be; 13.85.Qk.-- ISI Article Identifier: 000250140600014.-- ArXiv pre-print available at: http://arxiv.org/abs/0707.0085.-- et al.

Measurement of the cross section forW-boson production in association with jets inpp¯collisions ats=1.96  TeV

We present a measurement of the cross section for W-boson production in association with jets in p{bar p} collisions at {radical}s = 1.96 TeV. The analysis uses a data sample corresponding to an integrated luminosity of 320 pb{sup -1} collected with the CDF II detector. W bosons are identified in their electron decay channel and jets are reconstructed using a cone algorithm. For each W + {ge} n-jet sample (n = 1-4) we measure {sigma}(p{bar p} {yields} W + {ge} n-jet) x {Beta}(W {yields} e{nu}) with respect to the transverse energy E{sub T} of the nth-highest E{sub T} jet above 20 GeV, for a restricted W {yields} e{nu} decay phase space. The cross sections, corrected for all detector effects…

Outcomes of single versus double hormone receptor–positive breast cancer. A GEICAM/9906 sub-study

Abstract Background Retrospective data suggest better outcomes for patients with double hormonal receptor (oestrogen [ER] and progesterone receptor [PgR])–positive (dHR+) early breast cancer, compared with single hormonal receptor–positive, sHR+, (ER+/PgR– or ER–/PgR+) disease. Here, we evaluate the classification according to intrinsic subtypes and clinical outcomes of sHR+ versus dHR+ in HER2-negative breast cancer patients enrolled in GEICAM/9906 study ( NCT00129922 ). Methods Archival tumours were retrieved retrospectively for the analysis of ER, PgR and HER2 status and classified into intrinsic subtypes using the PAM50 gene expression assay. Disease-free survival (DFS) and overall surv…

First Measurement of Boson Production in Association with a Single Charm Quark in Collisions at

The authors present the first measurement of the production cross section of a W boson with a single charm quark (c) in p{bar p} collisions at {radical}s = 1.96 TeV, using soft muon tagging of c jets. In a data sample of {approx} 1.8 fb{sup -1}, recorded with the CDF II detector at the Fermilab Tevatron, they select events with W + 1 or 2 jets. They use the charge correlation between the W and the muon from the semileptonic decay of a charm hadron to extract the We signal. They measure {sigma}{sub Wc} (p{sub Tc} > 20 GeV/c, |{eta}{sub c}| < 1.5) x BR(W {yields} {ell}{nu}) = 9.8 {+-} 3.2 pb, in agreement with theoretical expectations.

Quantum chemical structure-activity relationships on β-carbolines as natural monoamine oxidase inhibitors

The electron density and the molecular electrostatic potential of the β-carbolines are studied using ab initioSTO-3G wave functions. The analysis was done from the point of view of a previous model built with monoamine oxidase substrates and irreversible inhibitors. The results confirm the usefulness of the model and make it possible to propose new precision to the molecular electrostatic potential patterns needed to have monoamine oxidase inhibitory activity.

Constraints on the unitarity triangle angleγfrom Dalitz plot analysis ofB0→DK+π−decays

The first study is presented of CP violation with an amplitude analysis of the Dalitz plot of B0→DK+π- decays, with D→K+π-, K+K-, and π+π-. The analysis is based on a data sample corresponding to 3.0 fb-1 of pp collisions collected with the LHCb detector. No significant CP violation effect is seen, and constraints are placed on the angle γ of the unitarity triangle formed from elements of the Cabibbo-Kobayashi-Maskawa quark mixing matrix. Hadronic parameters associated with the B0→DK∗(892)0 decay are determined for the first time. These measurements can be used to improve the sensitivity to γ of existing and future studies of the B0→DK∗(892)0 decay.

Observation of Exclusive Dijet Production at the Fermilab Tevatron p-pbar Collider

We present the first observation and cross section measurement of exclusive dijet production in pbar-p interactions, pbar + p --&gt; pbar + dijet + p. Using a data sample of 310 pb-1 collected by the Run II Collider Detector at Fermilab at sqrt{s}=1.96 TeV, exclusive cross sections for events with two jets of transverse energy ET &gt;= 10 GeV have been measured as a function of minimum ET(jet). The exclusive signal is extracted from fits to data distributions based on Monte Carlo simulations of expected dijet signal and background shapes. The simulated background distribution shapes are checked in a study of a largely independent data sample of 200 pb-1 of b-tagged jet events, where exclusi…

Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

The British journal of surgery 108(11), 1274-1292 (2021). doi:10.1093/bjs/znab183

Search for chargino-neutralino production inpp¯collisions ats=1.96  TeVwith high-pTleptons

We present a search for the associated production of charginos and neutralinos in pp collisions at s=1.96TeV. The data were collected at the Collider Detector at Fermilab (CDF II) and correspond to integrated luminosities between 0.7 and 1.0fb-1. We look for final states with one high-pT electron or muon, and two additional leptons. Our results are consistent with the standard model expectations, and we set limits on the cross section as a function of the chargino mass in three different supersymmetric scenarios. For a specific minimal supersymmetric standard model scenario with no slepton mixing, we set a 95% C.L. limit at 151GeV/c2. © 2008 The American Physical Society.

Search for new particles leading toZ+jetsfinal states inpp¯collisions ats=1.96  TeV

We present the results of a search for new particles that lead to a Z boson plus jets in p{bar p} collisions at {radical}s = 1.96 TeV using the Collider Detector at Fermilab (CDF II). A data sample with a luminosity of 1.06 fb{sup -1} collected using Z boson decays to ee and {mu}{mu} is used. We describe a completely data-based method to predict the dominant background from standard-model Z+jet events. This method can be similarly applied to other analyses requiring background predictions in multi-jet environments, as shown when validating the method by predicting the background from W+jets in t{bar t} production. No significant excess above the background prediction is observed, and a limi…

First study of the CP-violating phase and decay-width difference in Bs0→ψ(2S)ϕ decays

A time-dependent angular analysis of Bs0→ψ(2S)ϕ decays is performed using data recorded by the LHCb experiment. The data set corresponds to an integrated luminosity of 3.0fb−1 collected during Run 1 of the LHC. The CP-violating phase and decay-width difference of the Bs0 system are measured to be ϕs=0.23−0.28+0.29±0.02rad and ΔΓs=0.066−0.044+0.041±0.007ps−1, respectively, where the first uncertainty is statistical and the second systematic. This is the first time that ϕs and ΔΓs have been measured in a decay containing the ψ(2S) resonance.

Cross-section-constrained top-quark mass measurement from dilepton events at the tevatron

We report the first top quark mass measurement that uses a cross section constraint to improve the mass determination. This measurement is made with a dilepton $t\bar{t}$ event sample collected with the CDF II detector. From a data sample corresponding to an integrated luminosity of 1.2 fb$^{-1}$, we measure a top quark mass of $\rm{170.7^{+4.2}_{-3.9}(stat)\pm2.6(syst)}$ $\rm{\pm2.4(theory) GeV/{\it{c}}^{2}}$. The measurement without the cross section constraint results in a top quark mass of $\rm{169.7^{+5.2}_{-4.9}(stat)\pm3.1(syst) GeV/{\it{c}}^{2}}$.

Search for doubly charged higgs bosons with lepton-rlavor-violating decays involving τ leptons

We search for pair production of doubly charged Higgs particles (H(+/-+/-)) followed by decays into electron-tau (e tau) and muon-tau (mu tau) pairs using data (350 pb(-1)) collected from (p) over barp collisions at root s = 1.96 TeV by the CDF II experiment. We search separately for cases where three or four final-state leptons are detected, and combine results for exclusive decays to left-handed e tau (mu tau) pairs. We set an H(+/-+/-) lower mass limit of 114(112) GeV/c(2) at the 95% confidence level. RI Ruiz, Alberto/E-4473-2011; Robson, Aidan/G-1087-2011; De Cecco, Sandro/B-1016-2012; Prokoshin, Fedor/E-2795-2012; Azzi, Patrizia/H-5404-2012