0000000000343311

AUTHOR

Vincenzo Baldo

showing 5 related works from this author

Prevalence of Pneumococcal Serotypes in Community-Acquired Pneumonia among Older Adults in Italy: A Multicenter Cohort Study

2022

Pneumococcal community-acquired pneumonia (CAP) is a leading cause of mortality. Following the introduction of pneumococcal conjugate vaccines (PCVs) in children, a decrease in the burden of the disease was reported. In parallel, an increase in non-vaccine serotypes was also noted. The objective of this study was to assess the current serotype-specific epidemiology of pneumococci among Italian older adults hospitalized for CAP. A prospective study was conducted between 2017 and 2020 in four Italian regions. Subjects aged ≥65 years hospitalized with confirmed CAP were tested for pneumococci using both pneumococcal urinary antigen and serotype-specific urine antigen tests able to identify all…

pneumococcal conjugate vaccinecommunity-acquired pneumonia (CAP); older adults; pneumococcal conjugate vaccines; pneumococcal pneumonia; Streptococcus pneumoniaeMicrobiology (medical)Streptococcus pneumoniaepneumococcal pneumoniaVirologypneumococcal conjugate vaccinescommunity-acquired pneumonia (CAP)community-acquired pneumonia (CAP); <i>Streptococcus pneumoniae</i>; pneumococcal pneumonia; pneumococcal conjugate vaccines; older adultsSettore MED/42 - Igiene Generale E ApplicataMicrobiologyolder adultsMicroorganisms
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Evaluation of humoral and cellular response to four vaccines against COVID-19 in different age groups: A longitudinal study

2022

To date there has been limited head-to-head evaluation of immune responses to different types of COVID-19 vaccines. A real-world population-based longitudinal study was designed with the aim to define the magnitude and duration of immunity induced by each of four different COVID-19 vaccines available in Italy at the time of this study. Overall, 2497 individuals were enrolled at time of their first vaccination (T0). Vaccine-specific antibody responses induced over time by Comirnaty, Spikevax, Vaxzevria, Janssen Ad26.COV2.S and heterologous vaccination were compared up to six months after immunization. On a subset of Comirnaty vaccinees, serology data were correlated with the ability to neutr…

COVID-19 VaccinesAd26COVS1vaccines.SARS-CoV-2ImmunologyCOVID-19serologyViral VaccinesvaccinesHumansB-cell memory; COVID-19; cell-mediated immunity; serology; vaccinescell-mediated immunityImmunology and AllergyB-CELL MEMORY COVID-19 CELL-MEDIATED IMMUNITY SEROLOGY VACCINESB-cell memoryLongitudinal StudiesB-cell memory; COVID-19; cell-mediated immunity; serology; vaccines; Humans; Aged; COVID-19 Vaccines; Longitudinal Studies; Ad26COVS1; SARS-CoV-2; COVID-19; Viral VaccinesAgedFrontiers in Immunology
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Attitudes and beliefs on influenza vaccination during the covid-19 pandemic: Results from a representative italian survey

2020

The last 2019/20 northern hemisphere influenza season overlapped with the first wave of coronavirus disease 2019 (COVID-19) pandemic. Italy was the first western country where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread to a significant extent. In this representative cross-sectional survey, we aimed to describe some opinions and attitudes of the Italian general population towards both influenza vaccination and the COVID-19 pandemic, and to identify potential modifiers of the decision-making process regarding the uptake of the 2020/21 influenza vaccine. A total of 2543 responses were analyzed. Although most (74.8%) participants valued influenza vaccination positively …

0301 basic medicineCoronavirus disease 2019 (COVID-19)Influenza vaccineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyPopulationlcsh:MedicineInfluenza seasonArticleOddsSurvey.03 medical and health sciences0302 clinical medicinevaccineDrug DiscoveryPandemicMedicinePharmacology (medical)030212 general & internal medicineeducationSurveySettore MED/42 - IGIENE GENERALE E APPLICATAPharmacologyeducation.field_of_studyattitudesbusiness.industrylcsh:Rvirus diseasesCOVID-19InfluenzaVaccination030104 developmental biologyInfectious Diseasesinfluenza; COVID-19; vaccine; survey; vaccine hesitancy; attitudes; ItalyAttitudeItalyvaccine hesitancybusinessDemography
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Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Hemophilus influenzae type b vaccine; Infanrix™ hexa: T…

2014

Infant vaccination using 2-dose priming at 3 and 5 mo of age with a booster at 11–12 mo of age was pioneered in Italy. The 3-5-11 schedule is now used in a growing number of European countries. Infanrix™ hexa (DTPa-HBV-IPV/Hib, GlaxoSmithKline Vaccines) was first licensed for use in 2000 and has been the only pediatric hexavalent vaccine available since 2005. We reviewed available clinical trial data describing the immunogenicity of DTPa-HBV-IPV/Hib when administered at 3, 5, and 11 mo of age, and conducted an analysis of safety using global and Italian post-marketing surveillance data. In Italy, DTPa-HBV-IPV/Hib has a demonstrated safety record extending over a decade of use, it has been a…

safetybooster vaccination; combination vaccines; hexavalent vaccine; immunogenicity; Italy; primary vaccination; safety; Clinical Trials as Topic; Diphtheria-Tetanus-Pertussis Vaccine; Haemophilus Vaccines; Hepatitis B Vaccines; Humans; Italy; Poliovirus Vaccine Inactivated; Product Surveillance Postmarketing; Vaccination; Vaccines Combined; Medicine (all)Settore MED/42 - Igiene Generale e ApplicataImmunologySocio-culturaleReviewimmunogenicitySettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeprimary vaccinationProduct Surveillance PostmarketingmedicineImmunology and AllergyHumansHepatitis B VaccinesVaccines CombinedDiphtheria-Tetanus-Pertussis VaccineHaemophilus VaccinesPharmacologycombination vaccinesbooster vaccination; combination vaccines; hexavalent vaccine; immunogenicity; Italy; primary vaccination; safety; Medicine (all)Clinical Trials as TopicVaccinescombination vaccineTetanusbusiness.industryCombinedImmunogenicityPoliovirusDiphtheriaMedicine (all)VaccinationInactivatedHepatitis Bmedicine.diseaseVirologyProduct SurveillancePostmarketingClinical trialVaccinationPoliovirus Vaccinebooster vaccinationPoliovirus Vaccine InactivatedInfanrix hexaItalyhexavalent vaccine; primary vaccination; booster vaccination; Italy; combination vaccines; immunogenicity; safetybusinesshexavalent vaccine
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Impact of universal vaccination against varicella in Italy.

2014

In Italy, the introduction of Universal Varicella Vaccination (UVV) has been decided but postponed, as a national programme, until 2015, when data from Regions which have already implemented it will be available. Starting from 2003, eight Italian Regions (Basilicata, Calabria, Friuli Venezia Giulia, Apulia, Sardinia, Sicily, Tuscany and Veneto) have progressively introduced UVV, in their immunization programme, with different schedules in children aged 13–15 months and 5–6 years, currently a two-dose schedule is adopted by all Regions. In June 2013, an Interregional Group on Varicella Vaccination (IGVV) has been established in order to assess the effectiveness of varicella vaccination with …

MaleImmunization ProgramsHealth PolicyIncidenceimmunization coverageVaccinationUniversal Varicella VaccinationInfantnotificationsadverse events following varicella immunizationVaricellaChickenpox VaccineHospitalizationChickenpoxItalyChild PreschoolHumansFemaleHealth Services ResearchChildhospitalizationsResearch PaperHuman vaccinesimmunotherapeutics
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