0000000000343460

AUTHOR

Gregori Ujaque

0000-0001-5896-9998

showing 2 related works from this author

Gold(I)-catalyzed intermolecular oxyarylation of alkynes: unexpected regiochemistry in the alkylation of arenes.

2009

The reaction between acetylenes and sulfoxides, studied as a test case for gold-catalyzed intermolecular addition, provides the oxyarylation compounds 3 in good yields. Unpredictably, in all cases a single regioisomer arising from the electrophilic aromatic alkylation at the position adjacent to the sulfur atom is obtained instead of the expected Friedel−Crafts regioisomer. A new concerted mechanism based on DFT calculations is proposed to account for the products in this intermolecular gold(I)-catalyzed reaction.

inorganic chemicalsConcerted reactionOrganic ChemistryIntermolecular forceRegioselectivitychemistry.chemical_elementAlkylationPhotochemistryBiochemistrySulfurCatalysischemistryComputational chemistryElectrophileStructural isomerPhysical and Theoretical ChemistryOrganic letters
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ChemInform Abstract: Gold(I)-Catalyzed Intermolecular Oxyarylation of Alkynes: Unexpected Regiochemistry in the Alkylation of Arenes.

2010

The reaction between acetylenes and sulfoxides, studied as a test case for gold-catalyzed intermolecular addition, provides the oxyarylation compounds 3 in good yields. Unpredictably, in all cases a single regioisomer arising from the electrophilic aromatic alkylation at the position adjacent to the sulfur atom is obtained instead of the expected Friedel−Crafts regioisomer. A new concerted mechanism based on DFT calculations is proposed to account for the products in this intermolecular gold(I)-catalyzed reaction.

inorganic chemicalschemistryConcerted reactionIntermolecular forceElectrophileStructural isomerchemistry.chemical_elementRegioselectivityGeneral MedicineAlkylationSulfurMedicinal chemistryCatalysisChemInform
researchProduct