0000000000343563

AUTHOR

Giuseppe Penno

showing 3 related works from this author

Phenotyping normal kidney function in elderly patients with type 2 diabetes: a cross-sectional multicentre study

2018

AimsType 2 diabetes (T2D) accelerates the decline in glomerular function; however, some individuals do not develop chronic kidney disease despite advanced age and long-lasting T2D. We aimed to phenotype patients with T2D aged 80years or older who presented with a fully preserved kidney function.MethodsFrom an Italian population of 281,217 T2D outpatients, we collected data on demographics, anthropometrics, diabetes duration, HbA1c, fasting plasma glucose, lipids, liver enzymes, estimated glomerular filtration rate (eGFR), albumin excretion rate (AER), chronic complications, and medication use. We primarily compared patients with a fully preserved kidney function (eGFR>90ml/min/1.73m(2) and …

MaleEpidemiologyEndocrinology Diabetes and MetabolismType 2 diabetes030204 cardiovascular system & hematologyKidneyType 2 diabeteSettore MED/13 - Endocrinologia0302 clinical medicineEndocrinology80 and overMedicineDiabetic Nephropathies030212 general & internal medicineAged 80 and overeducation.field_of_studyType 2 diabetesGeneral MedicineEpidemiology; Insulin resistance; Nephropathy; Protective; Type 2 diabetesDiabetes and MetabolismPhenotypeLipotoxicityFemaleType 2HumanGlomerular Filtration Ratemedicine.medical_specialtyPopulationRenal functionEpidemiology; Insulin resistance; Nephropathy; Protective; Type 2 diabetes; Internal Medicine; Endocrinology Diabetes and Metabolism; EndocrinologyNephropathyEpidemiology; Insulin resistance; Nephropathy; Protective; Type 2 diabetes; Aged 80 and over; Diabetes Mellitus Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Phenotype; Internal Medicine; Endocrinology Diabetes and Metabolism; Endocrinology03 medical and health sciencesInsulin resistanceInternal medicineDiabetes mellitusDiabetes MellitusInternal MedicineHumanseducationAgedbusiness.industryInsulin resistancemedicine.diseaseNephropathyProtectiveDiabetes Mellitus Type 2Diabetic NephropathiebusinessKidney disease
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Effectiveness of dapagliflozin versus comparators on renal endpoints in the real world: A multicentre retrospective study.

2019

Aim: To evaluate the changes in renal endpoints in type 2 diabetes patients treated with dapagliflozin versus other glucose-lowering medications in routine clinical practice. Materials and Methods: DARWIN-T2D was a retrospective study conducted at 46 outpatient diabetes clinics in Italy. An automated software collected data on 17 285 patients who received dapagliflozin, glucagon-like peptide-1 receptor agonists, dipeptidyl peptidase-4 inhibitors, or gliclazide, 6751 of whom had a follow-up visit. We analysed changes in albumin excretion rate (AER) and estimated glomerular filtration rate (eGFR). Results: Patients who received dapagliflozin (n = 473) were younger, more obese, and had a poore…

MaleEndocrinology Diabetes and MetabolismType 2 diabetes030204 cardiovascular system & hematologyKidneychemistry.chemical_compound0302 clinical medicineEndocrinologyGlucosidesRetrospective StudieInterquartile rangeMedicineGliclazideDiabetic NephropathiesDapagliflozinPractice Patterns Physicians'Benzhydryl CompoundAged 80 and overdatabase researchMiddle AgedDiabetes and MetabolismTreatment OutcomeItalyFemaleOriginal Articletype 2 diabetesHumanmedicine.drugGlomerular Filtration Ratemedicine.medical_specialtyGlucosideDrug-Related Side Effects and Adverse ReactionsUrologyRenal function030209 endocrinology & metabolism03 medical and health sciencesDiabetes mellitusantidiabetic drug; dapagliflozin; database research; diabetic nephropathy; type 2 diabetes; Internal Medicine; Endocrinology Diabetes and Metabolism; EndocrinologyInternal MedicineHumansHypoglycemic AgentsBenzhydryl CompoundsAgedRetrospective Studiesantidiabetic drugtype 2 diabeteCreatinineHypoglycemic Agentbusiness.industrydiabetic nephropathyRetrospective cohort studyBiomarkerOriginal Articlesdapagliflozinmedicine.diseasechemistryDiabetes Mellitus Type 2Diabetic NephropathieDrug-Related Side Effects and Adverse ReactionbusinessBiomarkersDiabetes, obesitymetabolism
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40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

2004

0303 health sciencesmedicine.medical_specialtybusiness.industryEASDEndocrinology Diabetes and MetabolismHuman physiologymedicine.disease03 medical and health sciences0302 clinical medicineDiabetes mellitusFamily medicineInternal MedicineMedicinebusiness030217 neurology & neurosurgery030304 developmental biology
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