0000000000343839

AUTHOR

Susanne Knake

0000-0002-6298-0513

showing 3 related works from this author

First clinical postmarketing experiences in the treatment of epilepsies with brivaracetam: a retrospective observational multicentre study.

2019

ObjectivesBrivaracetam (BRV) is the latest approved antiepileptic drug and acts as a synaptic vesicle protein 2A ligand. The aim of the present study was to evaluate the efficacy and tolerability of BRV in the clinical setting.DesignRetrospective, observational multicentre study.SettingWe retrospectively collected clinical data of patients who received BRV in 10 epilepsy centres using a questionnaire that was answered by the reporting neurologist.ParticipantsData of 615 epilepsy patients treated with BRV were included in the study.Primary and secondary outcome measuresEfficacy regarding seizure frequency and tolerability of BRV were evaluated. Descriptive statistics complemented by X2 conti…

AdultMalemedicine.medical_specialtylevetiracetamefficacyBrivaracetam03 medical and health sciencesEpilepsyYoung Adult0302 clinical medicineInternal medicinemedicineProduct Surveillance PostmarketingHumansIn patient030212 general & internal medicine1506tolerabilityAdverse effectRetrospective StudiesOriginal ResearchSeizure frequencyEpilepsybrivaracetambusiness.industryGeneral MedicineMiddle Agedmedicine.diseasePyrrolidinonesadverse eventsTreatment OutcomeTolerabilityNeurologymonotherapy1713Observational studyAnticonvulsantsFemaleLevetiracetambusiness030217 neurology & neurosurgerymedicine.drugBMJ open
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Ictal functional TCD for the lateralization of the seizure onset zone—a report of two cases

2004

Ictal functional transcranial Doppler sonography (I-fTCD) was used to lateralize the ictal onset zone in the presurgical evaluation of two patients with temporal lobe epilepsy. In one patient, I-fTCD and ictal SPECT were performed simultaneously during EEG-monitoring. In both patients, results were concordant with the ictal SPECT findings, PET and semiology. I-fTCD seems to be an interesting new method to non-invasively lateralize the seizure onset zone with high temporal resolution. I-fTCD and SPECT may give complementary information to lateralize the seizure onset zone.

AdultMiddle Cerebral Arterymedicine.medical_specialtyUltrasonography Doppler TranscranialElectroencephalographyIctal-Interictal SPECT Analysis by SPMFunctional LateralityNeurosurgical ProceduresLateralization of brain functionTemporal lobeCentral nervous system diseaseEpilepsySeizuresmedicineHumansIctalTomography Emission-Computed Single-Photonmedicine.diagnostic_testbusiness.industryElectroencephalographySemiologymedicine.diseasenervous system diseasesEpilepsy Temporal Lobenervous systemNeurologyAnesthesiaFemaleNeurology (clinical)RadiologybusinessEpilepsy Research
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Satisfaction with and reliability of in-hospital video-EEG monitoring systems in epilepsy diagnosis – A German multicenter experience

2021

OBJECTIVE: To analyze satisfaction with and reliability of video-electroencephalography-monitoring systems (VEMS) in epilepsy diagnostics.; METHODS: A survey was conducted between December 2020 and January 2021 among German epilepsy centers using well-established customer satisfaction (CS) and quality assurance metrics.; RESULTS: Among 16 participating centers, CS with VEMS was low, with only 13% of customers actively recommending their system. Only 50% of users were satisfied with the overall performance of their VEMS, and a low 18% were satisfied with the manufacturer's customer service. User interface, software stability, lack of regular updates, and missing customer-oriented improvement…

TelemedicineComputer scienceData managementmedia_common.quotation_subjectVideo Recording050105 experimental psychology03 medical and health sciences0302 clinical medicineGermanyPhysiology (medical)Humans0501 psychology and cognitive sciencesQuality (business)Operations managementReliability (statistics)media_commonInpatientsEpilepsybusiness.industry05 social sciencesReproducibility of ResultsHealth technologyElectroencephalographyNeurophysiological MonitoringHospitalsTelemedicineSensory SystemsNeurologyVEMSPatient SatisfactionCustomer satisfactionNeurology (clinical)businessQuality assurance030217 neurology & neurosurgeryClinical Neurophysiology
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