0000000000343897

AUTHOR

Nadia Vassallo

showing 5 related works from this author

Neoclerodane Diterpenoids from Scutellaria pontica

1997

Seven novel neoclerodane diterpenoids, scupontins A-G, have been isolated from the Me2CO extract of the aerial parts of Scutellaria pontica (1-7), together with the known neoclerodanes scutalbin A and scutalpin M. Structures 1-7 were established by exhaustive NMR spectroscopic studies and chemical transformations. Scupontins A-D(1-4, respectively) and scupontins E (5)andF(6) possess unusual [(3¢S,3¢¢S)-3¢-[(3¢¢-acetoxybutyryl)oxy]butyryloxy and [(3¢S,3¢¢S,3¢¢¢S)- 3¢-[[3¢¢-[(3¢¢¢-hydroxybutyryl)oxy]butyryl]oxy]butyryl]oxy substituents, respectively, attached to the C-19 position of the neoclerodane framework. In the case of the 6R,7â-dibenzoate derivative 7 (scupontin G) its absolute config…

Pharmacologychemistry.chemical_classificationBicyclic moleculebiologyStereochemistryOrganic ChemistryAbsolute configurationPharmaceutical ScienceEpoxidebiology.organism_classificationAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryScutellariaMolecular MedicineDiterpeneChirality (chemistry)Derivative (chemistry)LactoneJournal of Natural Products
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A diterpenoid with antifeedant activity from Scutellaria rubicunda

1999

Abstract Two diterpenoids have been isolated from Scutellaria rubicunda subsp. linneana : (11 S ,13 S ,15 R and S , 16 R ,19 S )-6 α -acetoxy-19-tigloyloxy-2 α ,19;4 α ,18;11,16;15,16-tetraepoxy-neo-clerodan-15-ol (scutecyprol B) and (11 S ,13 S ,15 R and S , 16 R ,19 S )-6 α -acetoxy-2 α ,19;4 α ,18;11,16;15,16-tetra-epoxy-neo-cleroda-15,19,diol (scutalbin C). Both compounds were tested for antifeedant activity against larvae of some species of Lepidoptera. Scutecyprol B shows potent activity at 100 ppm.

biologyStereochemistryScutalbin CDiolBiological activityPlant ScienceGeneral MedicineHorticulturebiology.organism_classificationBiochemistryTerpenoidLepidoptera genitaliachemistry.chemical_compoundchemistryScutellariaDiterpeneMolecular BiologyPhytochemistry
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Neoclerodane Diterpenoids from Scutellaria polyodon

1997

Nine new neoclerodane diterpenoids, scupolins A−I, have been isolated from an Me2CO extract of the aerial parts of Scutellaria polyodon (3−11), together with the known neoclerodanes jodrellin B (1) and scutecolumnin A (2). Structures 3−11 were established by spectroscopic means and by comparison with closely related compounds.

Pharmacologychemistry.chemical_classificationbiologyStereochemistryOrganic ChemistryPharmaceutical ScienceEpoxidePharmacognosybiology.organism_classificationTerpenoidAnalytical Chemistrychemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryScutellariaMolecular MedicineOrganic chemistryHemiacetalDiterpeneLactoneJournal of Natural Products
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An ent-kaurane from Sideritis huber-morathii

1996

WOS: A1996VW86500030

biologyStereochemistryS-CaesareaPlant ScienceGeneral MedicineHorticultureLabiataebiology.organism_classificationBiochemistryTerpenoidchemistry.chemical_compoundchemistrySideritis Huber-MorathiiSideritis3718-Triacetyl-FoliolDiterpeneMolecular BiologyEnt kauraneEnt-Kaurane Diterpenoids
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Guaianolides and other terpenoids from Anthemis aetnensis

1997

Aerial parts of Anthemis aetnensis furnished the guaianolides hydruntinolide A and B and a number of new analogues, two new germacradienolides, 1-β-hydroxyarbusculin and the isofraxidin derived sesquiterpene ether 7-acetoxypectanone.

Anthemis aetnensisIsofraxidinEtherPlant ScienceGeneral MedicineHorticultureBiologySesquiterpeneBiochemistryTerpenoidchemistry.chemical_compoundchemistryBotanyOrganic chemistryMolecular BiologyPhytochemistry
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