0000000000343897
AUTHOR
Nadia Vassallo
Neoclerodane Diterpenoids from Scutellaria pontica
Seven novel neoclerodane diterpenoids, scupontins A-G, have been isolated from the Me2CO extract of the aerial parts of Scutellaria pontica (1-7), together with the known neoclerodanes scutalbin A and scutalpin M. Structures 1-7 were established by exhaustive NMR spectroscopic studies and chemical transformations. Scupontins A-D(1-4, respectively) and scupontins E (5)andF(6) possess unusual [(3¢S,3¢¢S)-3¢-[(3¢¢-acetoxybutyryl)oxy]butyryloxy and [(3¢S,3¢¢S,3¢¢¢S)- 3¢-[[3¢¢-[(3¢¢¢-hydroxybutyryl)oxy]butyryl]oxy]butyryl]oxy substituents, respectively, attached to the C-19 position of the neoclerodane framework. In the case of the 6R,7â-dibenzoate derivative 7 (scupontin G) its absolute config…
A diterpenoid with antifeedant activity from Scutellaria rubicunda
Abstract Two diterpenoids have been isolated from Scutellaria rubicunda subsp. linneana : (11 S ,13 S ,15 R and S , 16 R ,19 S )-6 α -acetoxy-19-tigloyloxy-2 α ,19;4 α ,18;11,16;15,16-tetraepoxy-neo-clerodan-15-ol (scutecyprol B) and (11 S ,13 S ,15 R and S , 16 R ,19 S )-6 α -acetoxy-2 α ,19;4 α ,18;11,16;15,16-tetra-epoxy-neo-cleroda-15,19,diol (scutalbin C). Both compounds were tested for antifeedant activity against larvae of some species of Lepidoptera. Scutecyprol B shows potent activity at 100 ppm.
Neoclerodane Diterpenoids from Scutellaria polyodon
Nine new neoclerodane diterpenoids, scupolins A−I, have been isolated from an Me2CO extract of the aerial parts of Scutellaria polyodon (3−11), together with the known neoclerodanes jodrellin B (1) and scutecolumnin A (2). Structures 3−11 were established by spectroscopic means and by comparison with closely related compounds.
An ent-kaurane from Sideritis huber-morathii
WOS: A1996VW86500030
Guaianolides and other terpenoids from Anthemis aetnensis
Aerial parts of Anthemis aetnensis furnished the guaianolides hydruntinolide A and B and a number of new analogues, two new germacradienolides, 1-β-hydroxyarbusculin and the isofraxidin derived sesquiterpene ether 7-acetoxypectanone.