0000000000347336
AUTHOR
J.l. Soriano-bru
Epidural anesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study
Abstract Objective The use of a test dose in epidural anesthesia is a safety recommendation. However, specificity and sensitivity of the drugs used with this indication have not been conclusive. The main objective of this study was to compare the effectiveness and the adverse effects of a simulated intravascular test dose of adrenaline, lidocaine and S(+)-ketamine. Material and methods A prospective, randomized, double blinded, placebo controlled study was designed. ASA I patients scheduled for elective surgery were included. These were randomized to the following study groups: S(+)-ketamine 0.5 mg kg −1 (S+K group), 5% lidocaine 1.5 mg kg −1 (L5% group), adrenaline 15 μg (ADR group), and p…
Single shot spinal anaesthesia with hypobaric bupivacaine for hip fracture repair surgery in the elderly. Randomized, double blinded comparison of 3.75 mg vs. 7.5 mg.
Arterial hypotension is the most frequent adverse effect of subarachnoid anaesthesia in the elderly sustaining a femoral proximal fracture. Decreasing the local anaesthetic dose reduces the incidence of hypotension but shortens sensory block duration that could be insufficient in some surgical procedures. Sensory block duration could be prolonged using hypobaric local anaesthetics. We evaluated whether low hypobaric bupivacaine doses were adequate for this type of surgery while maintaining the haemodynamic stability.A prospective, randomized, double blinded study was designed. Patients over 65 years old, sustaining traumatic hip fracture, were assigned to one of two groups: B0.5 group, hypo…
Anestesia epidural: dosis test intravascular simulada con S(+)-ketamina, lidocaína y adrenalina. Estudio prospectivo, aleatorizado, doble ciego, controlado con placebo
ResumenObjetivo La dosis test en anestesia epidural es una recomendacion de seguridad. La especificidad y sensibilidad de los farmacos empleados no ha resultado concluyente. Nuestro objetivo fue comparar la efectividad de adrenalina, lidocaina y S(+)-ketamina como dosis test intravascular simulada, asi como sus efectos adversos. Material y metodos Estudio prospectivo, aleatorizado, doble ciego, controlado con placebo. Pacientes ASA I, sometidos a cirugia electiva. Los grupos de estudio fueron (asignacion aleatoria): S(+)-ketamina 0,5 mg/kg-1 (grupo S + K), lidocaina 5% 1,5 mg/kg-1 (grupo L5%), adrenalina 15 μg (grupo ADR) y suero fisiologico 3 ml (grupo SF; grupo control). Se evaluaron los …