0000000000349174

AUTHOR

Wilko Spiering

showing 2 related works from this author

The Effects of Renal Denervation on Renal Hemodynamics and Renal Vasculature in a Porcine Model

2015

Rationale Recently, the efficacy of renal denervation (RDN) has been debated. It is discussed whether RDN is able to adequately target the renal nerves. Objective We aimed to investigate how effective RDN was by means of functional hemodynamic measurements and nerve damage on histology. Methods and Results We performed hemodynamic measurements in both renal arteries of healthy pigs using a Doppler flow and pressure wire. Subsequently unilateral denervation was performed, followed by repeated bilateral hemodynamic measurements. Pigs were terminated directly after RDN or were followed for 3 weeks or 3 months after the procedure. After termination, both treated and control arteries were prepar…

medicine.medical_specialtyPathologySympathetic Nervous SystemSwineUrologylcsh:MedicineHemodynamicsKidneyRenal CirculationLesionRenal ArteryAdventitiamedicine.arteryPressuremedicineAnimalsHumansRenal arterylcsh:ScienceDenervationKidneyMultidisciplinaryRenal circulationbusiness.industrylcsh:RHemodynamicsDenervationmedicine.anatomical_structureRenal blood flowHypertensionlcsh:Qmedicine.symptombusinessResearch ArticlePLOS ONE
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2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension

2018

International audience; These practice guidelines on the management of arterial hypertension are a concise summary of the more extensive ones prepared by the Task Force jointly appointed by the European Society of Hypertension and the European Society of Cardiology. These guidelines have been prepared on the basis of the best available evidence on all issues deserving recommendations; their role must be educational and not prescriptive or coercive for the management of individual subjects who may differ widely in their personal, medical and cultural characteristics. The members of the Task Force have participated independently in the preparation of these guidelines, drawing on their academi…

Malemedicine.medical_specialtyblood pressure measurementAdvisory Committees030204 cardiovascular system & hematologycombination therapyPotential conflict03 medical and health sciences0302 clinical medicineDevice therapyInternal medicineLifestyle interventionsecondary hypertensionInternal MedicineHumansMedicinedevice therapyadherence030212 general & internal medicineSocieties MedicalComputingMilieux_MISCELLANEOUSlifestyle interventionshypertension-mediated organ damageTask forcebusiness.industryGeneral Medicinespecial conditionsdrug therapy3. Good healthEuropeHypertensionBlood pressureCardiologyFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieCardiology and Cardiovascular Medicinebusinessblood pressure treatment thresholds and targets
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