0000000000349216
AUTHOR
Gp Rossi
Co-simulated Digital Twin on the Network Edge: the case of platooning
This paper presents an approach to create high fidelity Digital-Twin models for distributed multi-agent cyber-physical systems based on the combination of simulating components, generated from different modeling languages, each tailored for the specific domain of the subsystem. The approach specifically addresses the wireless communication domain, exploiting a Python module as a simulating component to evaluate the impact of network delay among the distributed elements of the system under analysis. A case study with a platoon of four vehicles following a leading car, all modeled in Simulink, is used to show the applicability of the approach, allowing the comparison between a Vehicle-to-Vehi…
Within-patient reproducibility of the aldosterone: renin ratio in primary aldosteronism.
The plasma aldosterone concentration:renin ratio (ARR) is widely used for the screening of primary aldosteronism, but its reproducibility is unknown. We, therefore, investigated the within-patient reproducibility of the ARR in a prospective multicenter study of consecutive hypertensive patients referred to specialized centers for hypertension in Italy. After the patients were carefully prepared from the pharmacological standpoint, the ARR was determined at baseline in 1136 patients and repeated after, on average, 4 weeks in the patients who had initially an ARR > or =40 and in 1 of every 4 of those with an ARR <40. The reproducibility of the ARR was assessed with Passing and Bablok and Demi…