0000000000349239

AUTHOR

Sunita Gupta

showing 2 related works from this author

Role of serum interleukin-6 in deciding therapy for multidrug resistant oral lichen planus

2015

Background: Oral lichen planus (OLP) is a T cell mediated immune response. T cells locally present in the involved tissues release cytokines like interleukin-6 (IL-6), which contributes to pathogenesis of OLP. Also IL-6 has been associated with multidrug resistance protein (MRP) expression by keratinocytes. Correspondingly, upregulation of MRP was found in OLP. We conducted this study to evaluate the effects of various drugs on serum IL-6 in OLP; and correlation of these effects with the nature of clinical response and resistance pattern seen in OLP lesions with various therapeutic modalities. Thus we evaluated the role of serum IL-6 in deciding therapy for multidrug resistant OLP. Material…

T cellOdontologíaPathogenesisPimecrolimusImmune systemstomatognathic systemMedicineInterleukin 6General DentistryOral Medicine and Pathologybiologybusiness.industryResearchmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludstomatognathic diseasesmedicine.anatomical_structureImmunologyUNESCO::CIENCIAS MÉDICASbiology.proteinBiomarker (medicine)MethotrexateOral lichen planusbusinessmedicine.drugJournal of Clinical and Experimental Dentistry
researchProduct

Mesenchymal chondrosarcoma of maxilla : a rare case report

2010

Mesenchymal chondrosarcoma (MC) is a rare variant of chondrosarcoma (CS) that accounts for upto 3-9% of all CS and has high predilection for the head and neck region. It is usually seen in younger age group compared to conventional CS and maxillary anterior alveolus is the most common site. The tumor is most unusual as it has been described as a particularly aggressive neoplasm with a high tendency for late recurrence and delayed metastasis. It is a biphasic tumor with areas comprising of spindle cell mesenchyme interspread with areas of chondroid differentiation. A 75 year old male presented to us as a painless mass in maxilla. Contrast enhanced computed tomography (CECT) revealed a lytic …

MalePathologymedicine.medical_specialtyMesenchymeMetastasisLesionmedicineHumansGeneral DentistryAgedMaxillary Neoplasmsbusiness.industryAlveolar processmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Mesenchymal chondrosarcomamedicine.anatomical_structureOtorhinolaryngologyMaxillaUNESCO::CIENCIAS MÉDICASSurgeryChondrosarcoma Mesenchymalmedicine.symptomChondrosarcomabusinessCalcification
researchProduct