0000000000350458
AUTHOR
Ferrari
EXAFS studies on the local structure of Er3+ ions in silica xerogels co-doped with aluminium
The local environment around Er3+ ions in wet and densified (at 900°C) silica xerogels (pure and co-doped with aluminium) has been studied at the Er L3-edge by X-ray absorption spectroscopy using the fluorescence detection technique. The radial distribution functions (RDF), reconstructed from X-ray absorption fine structure (EXAFS), show several changes in the local co-ordination of erbium ions upon densification: shortening of the Er-O and Er-Si/Al distances, decrease of the co-ordination numbers and broadening of the Er-O RDF. The effect of Al co-doping is clearly discerned by EXAFS in both the first and second co-ordination shells for densified gels and mainly in the second shell for wet…
Frovatriptan vs almotriptan for treatment of menstrual migraine: a double-blind, randomized, cross-over, multicenter Italian study
Results 67 of the 96 female patients of the intention-to-treat population of the main study had regular menstrual cycles and were thus included in this subgroup analysis. 77 migraine attacks classified as related to menses were treated with frovatriptan and 78 with almotriptan. Rate of pain relief at 2and 4-hrs was 36% and 53% for frovatriptan and 41% and 50% for almotriptan (p=NS between treatments). Rate of pain free at 2and 4-hrs was 19% and 47% with frovatriptan and 29% and 54% for almotriptan (p=NS). At 24-hrs, 62% of frovatriptanand 67% of almotriptan-treated patients had pain relief, while 60% vs. 67% were pain free (p=NS). Recurrence at 24-hrs was significantly (p<0.05) lower with f…