0000000000352178

AUTHOR

Zhengnan Wang

showing 2 related works from this author

Antibodies against MICA alleles in patients awaiting kidney transplantation and during the post-transplant course

2005

medicine.medical_specialtybiologybusiness.industryImmunologyGeneral Medicinemedicine.diseaseGastroenterologyPost transplantInternal medicinemedicinebiology.proteinImmunology and AllergyIn patientAlleleAntibodybusinessKidney transplantationHuman Immunology
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Detection of Anti-MICA Antibodies in Patients Awaiting Kidney Transplantation, during the Post-transplant Course, and in Eluates from Rejected Kidney…

2005

Previously we have reported on the development of antibodies against MICA alleles in kidney transplant recipients. These alloantibodies have now been determined using a new assay using Luminex beads bound to soluble recombinant MICA antigens produced in insect cells. In the present study we have analyzed sera from 85 kidney transplant recipients on the waiting list and 66 patients transplanted within the last 4 years and 59 acid eluates obtained from allograft nephrectomy specimens. Many of the patients in those groups were sensitized and some had previous transplants (waiting list: 15%; post-tx: 7.6%; eluates 22%) and their sera were found to contain anti-human leukocyte antigen (HLA) and …

AdultGraft RejectionMaleImmunologyHuman leukocyte antigenPathogenesisAntigenIsoantibodiesmedicineHumansImmunology and AllergyKidney transplantationKidneybiologyHistocompatibility Antigens Class IGeneral MedicineFlow Cytometrymedicine.diseaseKidney TransplantationRecombinant ProteinsTransplant rejectionstomatognathic diseasesmedicine.anatomical_structureImmunizationLuminescent MeasurementsImmunologybiology.proteinFemaleAntibodyHuman Immunology
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