0000000000352857

AUTHOR

Peter Fürst

showing 2 related works from this author

Environmental exposure to dioxins and polychlorinated biphenyls reduce levels of gonadal hormones in newborns: Results from the Duisburg cohort study

2006

Abstract Background Endocrine dysfunction related to the hypothalamic–pituitary–thyroid (HPT) and/or the hypothalamic–pituitary–gonadal axis (HPG) is being discussed as underlying developmental adversity of polychlorinated dibenzo- p -dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs). This study was done to evaluate effects related to the HPG axis. Methods A birth-cohort study was initiated in the year 2000. Healthy mother–infant pairs were recruited in the industrialized city of Duisburg, Germany. Dioxins, dioxin-like PCBs and six indicator PCBs were measured in maternal blood during pregnancy and in maternal milk. Testosterone and estradiol levels were measured in m…

AdultMalemedicine.medical_specialtyAdolescentHypothalamic–pituitary–gonadal axisDioxinsCohort StudiesSex FactorsPregnancyGermanyInternal medicinemedicineHumansTestosteroneEnvironmental medicineTestosteronePregnancyEstradiolMilk Humanbusiness.industryInfant NewbornPublic Health Environmental and Occupational HealthEnvironmental exposureFetal Bloodmedicine.diseaseNeurosecretory SystemsPolychlorinated BiphenylsEndocrinologyMaternal ExposureSex steroidPrenatal Exposure Delayed EffectsMultivariate AnalysisLinear ModelsFemalebusinessPolychlorinated dibenzofuransHormoneInternational Journal of Hygiene and Environmental Health
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Nitrate and nitrite in the diet: How to assess their benefit and risk for human health

2015

Nitrate is a natural constituent of the human diet and an approved food additive. It can be partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases blood pressure. This effect is associated with a reduced risk regarding cardiovascular disease, myocardial infarction, and stroke. Moreover, dietary nitrate has been associated with beneficial effects in patients with gastric ulcer, renal failure, or metabolic syndrome. Recent studies indicate that such beneficial health effects due to dietary nitrate may be achievable at intake levels resulting from the daily consumption of nitrate-rich vegetables. N-nitroso compounds are endogenously formed in humans. However…

risk analysisNitriteischemia-reperfusion injuryPhysiologyBenefitNitric OxideToxicologyNitratereduces blood-pressureNitric oxidechemistry.chemical_compoundNitrateRisk FactorsNeoplasmsVegetablesmedicineAnimalsHumansfluke opisthorchis-viverriniNitritenih-aarp dietNitritesToxicologiecolorectal-cancer riskCarcinogenRandomized Controlled Trials as TopicVLAGNitratesChemistryN-nitroso compoundsmedicine.diseasenitrosatable drug exposureDietMeat ProductsDisease Models Animaln-nitroso compoundsBlood pressureBiochemistryNitrosationMetabolic syndromecoronary-heart-diseaseRisk assessmentBiomarkersNitroso Compoundsinorganic nitrateneural-tube defectsFood ScienceBiotechnology
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