0000000000356051

AUTHOR

John

showing 2 related works from this author

Measurement of matter-antimatter differences in beauty baryon decays

2017

Differences in the behaviour of matter and antimatter have been observed in $K$ and $B$ meson decays, but not yet in any baryon decay. Such differences are associated with the non-invariance of fundamental interactions under the combined charge-conjugation and parity transformations, known as $C\!P$ violation. Using data from the LHCb experiment at the Large Hadron Collider, a search is made for $C\!P$-violating asymmetries in the decay angle distributions of $\Lambda^0_b$ baryons decaying to $p\pi^-\pi^+\pi^-$ and $p\pi^-K^+K^-$ final states. These four-body hadronic decays are a promising place to search for sources of $C\!P$ violation both within and beyond the Standard Model of particle…

Physics beyond the Standard ModelHadrontransformation [parity]General Physics and Astronomy7000 GeV-cms8000 GeV-cmsviolation [CP]decay [meson]01 natural sciencesHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - Experiment (hep-ex)antimatterscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]AntimatèriaDecays of bottom mesons Flavor symmetriesB mesonLHCb - Abteilung HintonPhysicsLarge Hadron Collider02 Physical Sciencesnew physicsCabibbo–Kobayashi–Maskawa matrixPhysicsparity: transformationParticle physicsFlavor symmetriesCharge conjugation parity time reversal and other discrete symmetrieDecays of bottom mesonsasymmetry: CPCERN LHC CollCP-VIOLATION; LAMBDA(B)meson: decayangular distribution [decay]AntimatterPhysical SciencesCP violationLHCcolliding beams [p p]Lambda/b0: hadronic decayParticle Physics - Experimentp p: scatteringParticle physicsAntimatterFluids & PlasmasPhysics MultidisciplinaryLambda/b0 --> p pi- K+ K-FOS: Physical scienceshadronic decay [Lambda/b0]Lambda/b0 --> p pi+ 2pi-CP [asymmetry]530Lambda/b0 --> p pi+ 2pi-Determination of Cabibbo-Kobayashi & Maskawa (CKM) matrix elementNONuclear physicsPhysics and Astronomy (all)LAMBDA(B)TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY0103 physical sciencesCP: violationdecay: angular distributionddc:530010306 general physicsLarge Hadron Collider (France and Switzerland)01 Mathematical SciencesScience & Technologycharge conjugation010308 nuclear & particles physicshep-exLambda/b0 --> p pi- K+ K-High Energy Physics::PhenomenologyGran Col·lisionador d'HadronsLHC-BHEPBaryonLHCbCP-VIOLATIONCKM matrixHadronic decays of baryonBottom baryons (|B|>0)High Energy Physics::ExperimentFísica de partículesExperimentsp p: colliding beamsstatisticalexperimental results
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Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

2016

Background BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using the largest available dataset, we determined whether MBCs arising in BRCA1/2 mutation carriers display specific pathologic features and whether these features differ from those of BRCA1/2 female BCs (FBCs). Methods We characterised the pathologic features of 419 BRCA1/2 MBCs and, using logistic regression analysis, contrasted those with data from 9675 BRCA1/2 FBCs and with population-based data from 6351 MBCs in the Surveillance, Epidemiology, and End Results (…

Male0301 basic medicineGenotype-phenotype correlationPathologygenotype-phenotype correlationsendocrine system diseasesSettore MED/06 - Oncologia MedicaFEATURESmale breast cancerGenotype-phenotype correlationsLogistic regressionHistologic grade610 Medical sciences MedicineBreast cancer0302 clinical medicineEpidemiologyMedicine and Health SciencesPathologypolycyclic compoundsskin and connective tissue diseasesPOPULATIONRISKeducation.field_of_studyBRCA1 ProteinMenSingle NucleotideMiddle Aged3. Good healthGRADE030220 oncology & carcinogenesisMale breast canceroncologyFemaleBreast NeoplasmResearch ArticleHumanAdultmedicine.medical_specialtyCARCINOMAGenotype–phenotype correlations3122 CancersPopulation610Breast NeoplasmsBRCA1/2; genotype-phenotype correlations; histologic grade; male breast cancer; pathology; cancer research; oncologyMale breast cancer BRCA1 BRCA2Polymorphism Single NucleotideCàncer de mamaBreast Neoplasms Male03 medical and health sciencesBreast cancerSDG 3 - Good Health and Well-beingBRCA1/2Journal ArticleCarcinomamedicineHumansGenetic Predisposition to DiseasePolymorphismeducationAgedNeoplasm StagingBRCA2 Proteinbusiness.industryOdds ratiohistologic grademedicine.diseaseConfidence intervalMale breast cancer030104 developmental biologyddc:161HomesMutationcancer researchpathologyBRCA1/2; Genotype-phenotype correlations; Histologic grade; Male breast cancer; Pathology; Adult; Aged; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; Breast Neoplasms Male; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mutation; Neoplasm Staging; Polymorphism Single Nucleotide; Oncology; Cancer Researchbusiness
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