0000000000358533
AUTHOR
H.m. Behre
Utilización del Integrated Semen Analysis System (ISAS)® para el análisis morfométrico espermático humano y su significado en las técnicas de reproducción asistida
Use of the integrated semen analysis system (ISAS ® ) for morphometric analysis and its role in assisted reproduction technologies
Supplementary Material for: Fertility Relevance Probability Analysis Shortlists Genetic Markers for Male Fertility Impairment
Impairment of male fertility is one of the major public health issues worldwide. Nevertheless, genetic causes of male sub- and infertility can often only be suspected due to the lack of reliable and easy-to-use routine tests. Yet, the development of a marker panel is complicated by the large quantity of potentially predictive markers. Actually, hundreds or even thousands of genes could have fertility relevance. Thus, a systematic method enabling a selection of the most predictive markers out of the many candidates is required. As a criterion for marker selection, we derived a gene-specific score, which we refer to as fertility relevance probability (FRP). For this purpose, we first categori…