0000000000362182

AUTHOR

Carlo Bova

showing 3 related works from this author

Validation of a Model for Identification of Patients at Intermediate to High Risk for Complications Associated With Acute Symptomatic Pulmonary Embol…

2015

For patients with acute symptomatic pulmonary embolism (PE), the Bova score classifies their risk for PE-related complications within 30 days after diagnosis. The original Bova score was derived from 2,874 normotensive patients with acute PE who participated in one of six prospective PE studies.We retrospectively assessed the validity of the Bova risk model in normotensive patients with acute PE diagnosed in an academic urban ED. Two clinician investigators used baseline data for the model's four prognostic variables to stratify patients into the three Bova risk stages (I-III) for 30-day PE-related complications. Intraclass correlation coefficient (ICC) and the κ statistic were used to asse…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyPrognostic variableIntraclass correlationBlood PressureCritical Care and Intensive Care MedicineRisk AssessmentHeart RateInternal medicine80 and overmedicineVentricular FunctionHumansStage (cooking)AgedRetrospective StudiesAged 80 and overFramingham Risk Scorebusiness.industryTroponin IReproducibility of ResultsRetrospective cohort studyMiddle AgedPrognosismedicine.diseasePulmonary embolismSurgeryAcute Disease; Aged; Aged 80 and over; Blood Pressure; Female; Heart Rate; Humans; Male; Middle Aged; Prognosis; Pulmonary Embolism; Reproducibility of Results; Retrospective Studies; Risk Assessment; Spain; Troponin I; Ventricular Function Right; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care Medicine; Cardiology and Cardiovascular MedicineRightSpainAcute DiseaseCohortVentricular Function RightFemalePulmonary EmbolismCardiology and Cardiovascular MedicineRisk assessmentbusinessChest
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Identification of intermediate-risk patients with acute symptomatic pulmonary embolism

2014

The identification of normotensive patients with acute pulmonary embolism (PE) at high risk of adverse PE-related clinical events (i.e. intermediate-risk group) is a major challenge. We combined individual patient data from six studies involving 2874 normotensive patients with PE. We developed a prognostic model for intermediate-risk PE based on the clinical presentation and the assessment of right ventricular dysfunction and myocardial injury. We used a composite of PE-related death, haemodynamic collapse or recurrent PE within 30 days of follow-up as the main outcome measure. The primary outcome occurred in 198 (6.9%) patients. Predictors of complications included systolic blood pressure …

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyVentricular Dysfunction RightHemodynamicsBlood PressureRecurrenceRisk FactorsInternal medicineHeart rateOdds RatiomedicineHumansProspective StudiesProspective cohort studyAgedRetrospective StudiesAged 80 and overbusiness.industryHemodynamicsRetrospective cohort studyOdds ratioMiddle AgedDecision Support Systems ClinicalPrognosismedicine.diseaseSurgeryPulmonary embolismTreatment OutcomeBlood pressureCardiologyFemaleCardiomyopathiesPulmonary EmbolismbusinessComplicationEuropean Respiratory Journal
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Aspirin After Oral Anticoagulants for Prevention of Recurrence in Patients with Unprovoked Venous Thromboembolism. the Warfasa STUDY

2011

Abstract Abstract 543 Background A recurrence occurs in 15–20% of patients with unprovoked venous thromboembolism (VTE) in the two years after the withdrawal of oral anticoagulant treatment. Extending anticoagulant treatment is effective but associated with increased bleeding risk. We assessed the efficacy and safety of aspirin for the prevention of VTE recurrence after a conventional course of oral anticoagulation. Methods Warfasa was an investigator-initiated double-blind randomized placebo-controlled event-driven study. Patients with a first-ever unprovoked VTE who had completed 6–12 months of oral anticoagulant treatment were randomized to receive aspirin, 100 mg daily, or placebo for a…

medicine.medical_specialtyAspirinbusiness.industryIncidence (epidemiology)ImmunologyHazard ratioCell BiologyHematologyPlaceboRelapse preventionBiochemistrySurgeryInternal medicinemedicineIn patientbusinessVenous thromboembolismOral anticoagulationmedicine.drugBlood
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