0000000000364579

AUTHOR

Sheila S. Gagnon

showing 9 related works from this author

Pre‐exercise whole‐body cooling decreases blood volume and oxygenated hemoglobin content in skeletal muscle during submaximal exercise (1106.7)

2014

Oxygenated Hemoglobinmedicine.medical_specialtybusiness.industrySkeletal muscleBlood volumeSubmaximal exerciseBiochemistryPre exercisemedicine.anatomical_structureInternal medicineGeneticsmedicineCardiologyPhysical therapyWhole bodybusinessMolecular BiologyBiotechnologyThe FASEB Journal
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The effects of skin and core tissue cooling on oxygenation of the vastus lateralis muscle during walking and running

2016

Skin and core tissue cooling modulates skeletal muscle oxygenation at rest. Whether tissue cooling also influences the skeletal muscle deoxygenation response during exercise is unclear. We evaluated the effects of skin and core tissue cooling on skeletal muscle blood volume and deoxygenation during sustained walking and running. Eleven male participants walked or ran six times on a treadmill for 60 min in ambient temperatures of 22°C (Neutral), 0°C for skin cooling (Cold 1), and at 0°C following a core and skin cooling protocol (Cold 2). Difference between oxy/deoxygenated haemoglobin ([diffHb]: deoxygenation index) and total haemoglobin content ([tHb]: total blood volume) in the vastus lat…

MalespectroscopyVastus lateralis musclePhysical Therapy Sports Therapy and RehabilitationBlood volumeWalking030204 cardiovascular system & hematologythermal responsesQuadriceps MuscleRunningHemoglobinsYoung Adult03 medical and health sciencesOxygen Consumption0302 clinical medicinemedicineHumansOrthopedics and Sports MedicineTreadmillta315heat economy (metabolism)DeoxygenationCore (anatomy)Blood VolumeSpectroscopy Near-InfraredChemistrySkeletal muscle030229 sport sciencesGas exchangeOxygenationAnatomyhemoglobinCold Temperaturemedicine.anatomical_structureAnesthesiaexercise (people)Energy MetabolismSkin Temperatureear-infrared spectroscopyBody Temperature RegulationJournal of Sports Sciences
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Fuel selection during short-term submaximal treadmill exercise in the cold is not affected by pre-exercise low-intensity shivering.

2014

Exercise and shivering rely on different metabolic pathways and consequently, fuel selection. The present study examined the effects of a pre-exercise low-intensity shivering protocol on fuel selection during submaximal exercise in a cold environment. Nine male subjects exercised 4 times for 60 min at 50% (LOW) or 70% (MOD) of their peak oxygen consumption on a motorized treadmill in a climatic chamber set at 0 °C with (SHIV) and without (CON) a pre-exercise cooling protocol, inducing low-intensity shivering. Thermal, cardiorespiratory and metabolic responses were measured every 15 min whereas blood samples were collected every 30 min to assess serum nonesterified fatty acids (NEFA), glyce…

Malemedicine.medical_specialtyTime FactorsPhysiologyEndocrinology Diabetes and MetabolismCarbohydrate metabolismNorepinephrine (medication)Young AdultAnimal scienceNEFAPhysiology (medical)medicineHumansExercise physiologyTreadmillExerciseNutrition and DieteticsChemistryShiveringCardiorespiratory fitnessGeneral MedicineSurgeryCold TemperatureCatecholamineShiveringExercise Testmedicine.symptomEnergy Metabolismmedicine.drugApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
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Microdialysis-Assessed Exercised Muscle Reveals Localized and Differential IGFBP Responses to Unilateral Stretch Shortening Cycle Exercise

2020

Microdialysis allows for a preview into local muscle metabolism and can provide physiological insight that blood measurements cannot. Purpose: To examine the potential differential IGF-I system regulation in interstitial fluid during unilateral stretch shortening cycle exercise. Methods: 10 men (26 ± 7 year) performed unilateral jumping [stretch shortening cycle (SSC) exercise at 50% of optimal jump height] until volitional fatigue on a sled apparatus. Biological sampling took place using a catheter inserted into an antecubital vein (serum), and 100 kDa microdialysis probes inserted into the thigh muscle of each exercise/control leg (dialysate). Serum was drawn before (Pre; −3 h) and after …

AdultMale0301 basic medicinemedicine.medical_specialtyMicrodialysismicrodialysismuscleinterstitial fluidAntecubital veinEndocrinology Diabetes and Metabolismlihakset030209 endocrinology & metabolismmedicine.disease_causelcsh:Diseases of the endocrine glands. Clinical endocrinologyStretch shortening cycleYoung Adult03 medical and health sciencesEndocrinology0302 clinical medicineJumpingInterstitial fluidMuscle Stretching ExercisesInternal medicinemedicineHumansInsulin-Like Growth Factor IMuscle SkeletallihassolutOriginal Researchlcsh:RC648-665business.industryendokrinologiaRepeated measures designDifferential regulationIGF-IInsulin-Like Growth Factor Binding Proteins030104 developmental biologyEndocrinologyStretch-Shortening Cycle Exercisevoimaharjoittelustretch shortening cycle exercisebinding proteinsbusinessFrontiers in Endocrinology
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Active recovery shows favorable IGF-I and IGF binding protein responses following heavy resistance exercise compared to passive recovery

2019

IGF-I and IGFBPs have important physiological modulatory effects and this study sought to examine the influence of active vs. passive recovery following a heavy resistance exercise on IGF-I and IGF binding protein (IGFBP) recovery responses. It was hypothesized that increased IGF-I and decreased inhibitory IGFBPs during active recovery may be reflective of cascades promoting physiological recovery. 18 untrained men ((AR n = 7, PR n = 11), age: 26 ± 4 years, height: 174 ± 8 cm, body mass: 75 ± 13 kg) performed either a protocol-specific 10 × 10 × 30% 1RM active (AR) or passive recovery (PR) session following a heavy resistance exercise session performed on a leg press device (10 × 10 1RM). M…

AdultMale0301 basic medicinemedicine.medical_specialtyEndocrinology Diabetes and MetabolismPassive recovery030209 endocrinology & metabolismIsometric exercise03 medical and health sciences0302 clinical medicineEndocrinologyInternal medicinemedicineHumansInsulin-Like Growth Factor ILeg pressMorningbusiness.industryBinding proteinResistance trainingResistance TrainingRecovery of FunctionInsulin-Like Growth Factor Binding Proteins030104 developmental biologyEndocrinologyFemalebusinessGrowth Hormone & IGF Research
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The Effects of Cold Exposure on Leukocytes, Hormones and Cytokines during Acute Exercise in Humans

2014

The purpose of the study was to examine the effects of exercise on total leukocyte count and subsets, as well as hormone and cytokine responses in a thermoneutral and cold environment, with and without an individualized pre-cooling protocol inducing low-intensity shivering. Nine healthy young men participated in six experimental trials wearing shorts and t-shirts. Participants exercised for 60 min on a treadmill at low (LOW: 50% of peak VO2) and moderate (MOD: 70% VO2peak) exercise intensities in a climatic chamber set at 22°C (NT), and in 0°C (COLD) with and without a pre-exercise low-intensity shivering protocol (SHIV). Core and skin temperature, heart rate and oxygen consumption were col…

MaleMuscle PhysiologyHydrocortisonePhysiologylcsh:MedicineCardiovascular PhysiologyNorepinephrine0302 clinical medicineHeart RateImmune PhysiologySex Hormone-Binding GlobulinMedicine and Health SciencesLeukocytesMedicineTestosteroneInsulin-Like Growth Factor ITreadmilllcsh:Scienceta315MultidisciplinaryThermogenesista314116. Peace & justiceCold shock responseEpinephrineShiveringCytokinesmedicine.symptomEnvironmental HealthResearch ArticleBody Temperature Regulationmedicine.drugAdultmedicine.medical_specialtyEpinephrineleukocytesPhysical ExertionAdrenocorticotropic hormoneYoung Adult03 medical and health sciencesAdrenocorticotropic Hormoneeffects of exerciseInternal medicineHeart rateHumansSports and Exercise MedicineExerciseHydrocortisoneEndocrine Physiologybusiness.industryCold-Shock Responsesytokiinitlcsh:RBiology and Life Sciences030229 sport sciencesMolecular DevelopmenthormonitHealth CareEndocrinologylcsh:QPhysiological Processesbusiness030217 neurology & neurosurgeryDevelopmental BiologyHormonePLoS ONE
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Human skeletal muscle type 1 fibre distribution and response of stress-sensing proteins along the titin molecule after submaximal exhaustive exercise.

2017

Early responses of stress-sensing proteins, muscle LIM protein (MLP), ankyrin repeat proteins (Ankrd1/CARP and Ankrd2/Arpp) and muscle-specific RING finger proteins (MuRF1 and MuRF2), along the titin molecule were investigated in the present experiment after submaximal exhaustive exercise. Ten healthy men performed continuous drop jumping unilaterally on a sledge apparatus with a submaximal height until complete exhaustion. Five stress-sensing proteins were analysed by mRNA measurements from biopsies obtained immediately and 3 h after the exercise from exercised vastus lateralis muscle while control biopsies were obtained from non-exercised legs before the exercise. Decreased maximal jump h…

0301 basic medicineANKRD2AdultMalemedicine.medical_specialtyANKRD1HistologyAdolescentVastus lateralis musclePhysical ExertionMuscle Proteinslihaksetmedicine.disease_causetuki- ja liikuntaelimet03 medical and health sciencesYoung Adult0302 clinical medicineJumpingHsp27Internal medicinemedicinestress-sensing proteinsHumanstitinConnectinMolecular BiologyExerciseurheiluvammatbiologySkeletal muscleCell BiologyAnatomyhuman skeletal muscleMedical Laboratory Technology030104 developmental biologymedicine.anatomical_structureEndocrinologyMuscle Fibers Slow-Twitchbiology.proteinexercise induced muscle damageTitinAnkyrin repeat030217 neurology & neurosurgeryHistochemistry and cell biology
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Basal Endogenous Steroid Hormones, Sex Hormone-Binding Globulin, Physical Fitness, and Health Risk Factors in Young Adult Men.

2018

Purpose: Few large-scale population-based studies have adequately examined the relationships between steroid hormones, health status and physical fitness. The purpose of the study was to describe the relationship of serum basal endogenous steroid hormones (testosterone, TES; empirical free testosterone, EFT; cortisol, COR) and sex hormone-binding globulin (SHBG) to body composition, cardiovascular risk factors, and physical fitness in young healthy men. Methods: Male reservists (25 ± 4 years, N = 846) participated in the study. Basal TES, EFT, COR, and SHBG were measured in morning fasted blood. Stepwise regression analyses were used to examine associations between individual hormones to fo…

sukupuolihormonitPhysiologyfood and beveragescardiovascular healthliikuntacortisolwaist circumferencehormonitaerobic capacityfyysinen kuntoterveysvaikutuksettestosteronephysical fitnessmiehetaerobinen suorituskykysex hormone-binding globulintestosteronisteroiditterveysriskitfyysinen aktiivisuusOriginal ResearchFrontiers in physiology
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Valmentajat avainasemassa nuorten polvivammojen ehkäisyssä

2022

Eturistisidevammojen ennaltaehkäisyyn tähtäävä hermo-lihasharjoitusohjelma voidaan toteuttaa osana alkulämmittelyä ennen harjoittelua. nonPeerReviewed

harjoitusmenetelmäteturistisideurheiluvammatnuoretharjoitteluennaltaehkäisyvalmennusbiomekaniikka
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