0000000000365232

AUTHOR

Simonetta Tagliavini

showing 2 related works from this author

Premature ovarian senescence and a high miscarriage rate impair fertility in women with HCV

2017

Background & Aims Premenopausal women who are HCV positive (HCV+) have failing ovarian function, which is likely to impact their fertility. Thus, we investigated the reproductive history, risk of infertility, and pregnancy outcomes in women of childbearing age who were HCV+. Methods Three different groups were studied: (1) Clinical cohort: 100 women who were HCV+ and also had chronic liver disease (CLD), age matched with 50 women who were HBV+ with CLD and with 100 healthy women; all women were consecutively observed in three gastroenterology units in hospitals in Italy; (2) 1,998 women who were HCV+ and enrolled in the Italian Platform for the Study of Viral Hepatitis Therapies (PITER)…

Anti-Mullerian hormone; Antiviral therapy; HBV; HCV; Sustained viral response; HepatologyInfertilitymedicine.medical_specialtySustained viral responsemedia_common.quotation_subjectFertilityAnti-Müllerian hormoneAntiviral therapyMiscarriage03 medical and health sciences0302 clinical medicineHBVMedicineProspective cohort studymedia_commonGynecologyAnti-Müllerian hormone Antiviral therapy HBV HCV Sustained viral response030219 obstetrics & reproductive medicineHepatologybusiness.industryObstetricsAnti-Müllerian hormone; Antiviral therapy; HBV; HCV; Sustained viral responseAnti-Mullerian hormonemedicine.diseaseAnti-Müllerian hormoneGestational diabetesCohortHCV030211 gastroenterology & hepatologyAnti-Müllerian hormone; Antiviral therapy; HBV; HCV; Sustained viral response; HepatologybusinessLive birthCell aging
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Reproductive status is associated with the severity of fibrosis in women with hepatitis C.

2012

Introduction Chronic hepatitis C is the main cause of death in patients with end-stage liver disease. Prognosis depends on the increase of fibrosis, whose progression is twice as rapid in men as in women. Aim of the study was to evaluate the effects of reproductive stage on fibrosis severity in women and to compare these findings with age-matched men. Materials and Methods A retrospective study of 710 consecutive patients with biopsy-proven chronic hepatitis C was conducted, using data from a clinical database of two tertiary Italian care centers. Four age-matched groups of men served as controls. Data about demographics, biochemistry, liver biopsy and ultrasonography were analyzed. Contrib…

Liver CirrhosisMalemedicine.medical_specialtyGastroenterology and hepatologyLiver CirrhosiPhysiologylcsh:MedicineViral diseasesChronic hepatitis CSeverity of Illness IndexHepatitisLiver diseaseEndocrinologyFibrosisRetrospective StudieSeverity of illnessmedicinegenderHumansReproductive EndocrinologyChronic hepatitis C; genderlcsh:ScienceTestosteroneLiver diseasesRetrospective StudiesGynecologyMultidisciplinarymedicine.diagnostic_testbusiness.industrylcsh:RCase-control studyHepatitis Cmedicine.diseaseHepatitis CMenopauseInfectious hepatitisCirrhosisLiver biopsyCase-Control StudiesMedicineInfectious diseasesWomen's HealthFemalelcsh:QbusinessCase-Control StudieInfertility FemaleResearch ArticleHumanPLoS ONE
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