0000000000367826
AUTHOR
P. Kaatsch
showing 7 related works from this author
PanCareLIFE
2018
Aims: Survival after cancer diagnosed during childhood or adolescence continues to improve with new treatments and supportive therapies. Optimal long-term care requires that risks to vulnerable organs are clearly defined and translated into guidelines that are implemented into practice. PanCareLIFE is a pan-European consortium that addresses survivorship issues comprising fertility, hearing impairment and quality of life. This article describes the scientific basis of PanCareLIFE's studies.Methods: PanCareLIFE involves 17 partner institutions from eight European countries, with additional 11 data providers from five other countries. Study designs and methods include molecular genetic, cohor…
Datenaustausch mit Hilfe von Bildschirmtext im Rahmen Eines Bundesweiten Registers für Malignome im Kindesalter
1985
Am Institut fur Medizinische Statistik und Dokumentation der Universitat Mainz (IMSD) werden seit Anfang 1980 alle bei Kindern auftretenden Malignomerkrankungen bundesweit zentral erfast (vergl. MICHAELIS,S. 219 bis 228 in diesem Band). Da das Projekt sowohl den Charakter eines bevolkerungsbezogenen, epidemiologischen Registers, als auch die Funktion eines klinischen Krebs- und Nachsorgeregisters hat, sind die Anforderungen, die an das Dokumentationssystem gestellt werden, von sehr unterschiedlicher Natur.
Epidemiologie von Hirntumoren im Kindesalter
2000
The German Childhood Cancer Registry (GCCR) was established in 1980. From 1980 to 1997 4,447 CNS tumours in children below 15 years of age have been reported to the registry. From 1988 to 1997 the average annual incidence was 2.5/100,000 children. This corresponds to 19.2% of the registered diseases. Compared with incidence rates reported from other developed countries one can estimate that there is about 25% underreporting of CNS tumours in the GCCR. This is in contrast to the relatively complete ascertainment of other childhood malignancies (above 95%). Based on 3012 incident cases from 1988 to 1997 the Kaplan-Meier-estimate of 5-year-survival probability is 65% for all CNS tumours and 54…
Modelle für Inzidenzschätzungen bei einer Bevölkerung mit stark variierender Altersstruktur - dargestellt am Beispiel des Registers für Malignome im …
1988
Am Institut fur Medizinische Statistik und Dokumentation der Universitat Mainz wird seit 1980 ein Register fur Malignome im Kindesalter gefuhrt, in dem alle vor dem 15. Lebensjahr auftretenden bosartigen Erkrankungen aus der Bundesrepublik erfast werden (1,2). Infolge der ausgesprochen guten Kooperation innerhalb der padiatrischen Onkologie, die sich unter anderem mit der Durchfuhrung von 15 multizentrischen Therapiestudien belegen last, ist es gelungen, eine nahezu flachendeckende Erfassung zu realisieren. Neben dem Ziel, ein kliniksorientiertes Register zu schaffen, konnte auch ein bevolkerungsbezogenes epidemiologisches Krebsregister aufgebaut werden, das es ermoglicht, deskriptive und a…
Subtype-specific incidence of testicular cancer in Germany: a pooled analysis of nine population-based cancer registries.
2009
Summary Comparisons of incidence estimates of testicular cancer subtypes beyond seminoma and non-seminoma are virtually missing in the epidemiologic literature. We analysed incidence data from population-based German cancer registries to provide subtype-specific incidences of testicular cancer. We pooled data from nine cancer registries from 1998 to 2003. We estimated incidence and mortality time trends of West and East Germany. Incidence and mortality were standardized by the European standard population. The annual percentage incidence change from 1961 through 1989 was 4.9% in East Germany and 3.0% from 1970 through 2004 in Saarland. Incidence increases were the most pronounced among adol…
Survival of European children and young adults with cancer diagnosed 1995-2002
2009
This study analyses survival in 40,392 children (age 0-14 years) and 30,187 adolescents/young adults (age 15-24 years) diagnosed with cancer between 1995 and 2002. The cases were from 83 European population-based cancer registries in 23 countries participating in EUROCARE-4. Five-year survival in countries and in regional groupings of countries was compared for all cancers combined and for major cancers. Survival for 15 rare cancers in children was also analysed. Five-year survival for all cancers combined was 81% in children and 87% in adolescents/young adults. Between-country survival differences narrowed for both children and adolescents/young adults. Relative risk of death reduced signi…
Geographical variability in survival of European children with central nervous system tumours
2017
Survival for childhood central nervous system (CNS) tumours varies across Europe, partly because of the difficulty of distinguishing malignant from non-malignant disease. This study examines bias in CNS tumours survival analysis to obtain the reliable and comparable survival figures. We analysed survival data for about 15, 000 children (age <15) diagnosed with CNS between 2000 and 2007, from 71 population- based cancer registries in 27 countries. We selected high- quality data based on registry- specific data quality indicators and recorded observed 1-year and 5-year survival by countries and CNS entity. We provided age- adjusted survival and used a Cox model to calculate the hazard ratios …