0000000000368412

AUTHOR

Ferdinand Hundt

showing 3 related works from this author

The determination of the DNA base composition in 19 species of adriatic sponges with high-pressure liquid cation-exchange chromatography.

1976

Abstract The (adenine + thymine)/(guanine + cytosine) base ratios of 19 species of adriatic sponges have been determined by high-pressure liquid cation-exchange chromatography. The base ratios vary from 1.49 (Mycale massa) to 0.63 (Hippospongia communis) according to an (A+T) content of 59.7 and 38.6 mol%, respectively. The DNAs of sponges of the order Keratosa showed marked differences in their (A +T) contents (39.5 to 58.8 mol%) whereas those of Tetractinellida and Halichondrina were nearly identical (39.3 to 40.8 and 49.5 to 49.8 mol%, respectively). The 5-methylcytosine (5MC) content was determined in 8 sponge DNAs by a semiquantitative method. The values differed from 0.8 to 2.2 mol% o…

chemistry.chemical_classificationChromatographyBase (chemistry)GuanineIon chromatographyDeoxyribonucleosidesDNABiologybiology.organism_classificationChromatography Ion ExchangeHigh-performance liquid chromatographyGeneral Biochemistry Genetics and Molecular BiologyThyminePoriferachemistry.chemical_compoundSpongechemistryAnimalsComposition (visual arts)CytosineChromatography High Pressure LiquidZeitschrift fur Naturforschung. Section C, Biosciences
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Fondaparinux and enoxaparin in comparison to unfractionated heparin in preventing thrombus formation on mechanical heart valves in an ex vivo rabbit …

2003

SummaryThe aim of the present study was to investigate the efficacy of three different parenterally administered anticoagulants for the prevention of thrombus formation on artificial heart valves in an experimental rabbit model.Unfractionated heparin was administered intravenously in group I (n = 10), Enoxaparin subcutaneously in group II (n = 10), fondaparinux intravenously in group III (n = 10), and no medication was administered to group IV (n = 9). Leaflets from Sulzer Carbomedics bileaflet mechanical heart valves were placed in a flow chamber. The flow chamber was filled with blood in a continuous circulation between the carotid artery and the jugular vein.In group IV the flow chamber …

MaleArtificial heart valvemedicine.drug_classmedicine.disease_causeFondaparinuxPolysaccharidesmedicineAnimalsHeart valveEnoxaparinThrombusHeparinbusiness.industryAnticoagulantAnticoagulantsThrombosisHematologyHeparinmedicine.diseaseFondaparinux SodiumMicroscopy Electronmedicine.anatomical_structureFondaparinuxHeart Valve ProsthesisAnesthesiaBlood Coagulation TestsRabbitsbusinessEnoxaparin sodiummedicine.drugThrombosis and Haemostasis
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Effects of isoflurane on the Dnase I activity in an isolated enzyme preparation and on the Dnase I-G actin complex

1991

Effects of isoflurane on the DNase I activity in an isolated enzyme preparation and in the DNase I-globular (G) actin complex were investigated. DNase I, DNase I-G actin complex, and G actin were exposed to various (0.2–4.0 vol%) isoflurane concentrations for 180 min. Thereafter, DNase I activity was determined. DNase I activity was inhibited in relation to time and concentration of isoflurane exposure. At concentrations ranging from 0.2 to 1.0 vol% of isoflurane inactive DNase I was activated in the DNase I-G actin complex. The DNase I inhibitor G actin showed a reduced capability to inhibit DNase I following isoflurane exposure. Albumin can inhibit the DNase I inactivation possibly by com…

chemistry.chemical_classificationProtein DenaturationIsofluraneAlbuminAbsorption (skin)BuffersToxicologyMolecular biologyActinschemistry.chemical_compoundEnzymechemistryBiochemistryIsofluranemedicineAnimalsDeoxyribonuclease ICattlePancreasDNAActinDNA Damagemedicine.drugJournal of Biochemical Toxicology
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