Systemic Review: Ozone: A Potential New Chemotherapy

In the last sixty years, publications in reputed journals have shown the preclinical positive effect of ozone gas in cancer cells. However, the translation of these results into clinical practice is far away from success. A comprehensive approach is necessary for this, and oncologists and researchers need guidance from medical specialists with in-depth knowledge of ozone in medicine. In this article, we review the evidence around this question and suggest different potential research lines to those interested in this exciting field.

The efficacy of intra-articular PRP, ozone and ozone+PRP injections in patients with osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and some joints are effected more than others. The prevalence of OA increases with age and it represents the major problem for functional impairment in older patients. Non-surgical treatment with oral drugs is not suitable for many patients suffering from gastric disorders, high blood pressure or different heart diseases. Intra-articular injections are a promising solution in these cases.
 This study was performed to compare the efficacy and safety of ozone injections, PRP (platelet rich plasma) injections and combined ozone plus PRP injections in patients with symptomatic knee OA. 
 120 patients were diagnosed of OA accordi…

The diamod tip.

This issue 5 is devoted to spine diseases that can be treated or improved by using medical ozone. Dr. Alberto Alexandre compiled during 2015 and 2016 a number of papers from experienced authors in order to prepare a monographic issue but found a lot of difficulty in publishing it. I offered him our Journal to publish these scientific works and he agreed. 
 
 COVID-19 pandemic has produce a huge increase in publishing time for all journals but we finally have been able to produce this issue. Due to the delay in its publication, some papers have been published by their authors in other journals. 
 
 We are hardly working in issue 6 that will be opened for different topics …

Editorial issue 2

It has been a very long trip since I wrote my last editorial. The first issue of the Journal received a strong welcome from all over the world in the beginning of 2016, but there was something missing that drove us to a winding road that ended in an even stronger situation: the support of the University of Valencia’s Publication Service (UVPS). The missing thing in the first issue was the DOI (Digital Object Identifier). All the online journals have a DOI to identify the papers and allow a permanent link to them. Each DOI is unique for each paper. We look for a DOI provider in our environment and found the UVPS to offer DOIs for free to their teachers. As I am one of them, I went to ask for…

Correcting Misinformation about the Science and Practice of Evidence-Based, Safe and Effective Ozone Therapy.

Good prospects

This third issue compiles the papers sent during 2017 and some others sent in 2018, so I apologise all the authors for the delay and thank them for their patience. The 4th issue will be devoted to be the proceeding of the World Congress organized by Dr Lamberto Re in Ancona - Italy in 2017 and will be published by Summer-19. Issue number 5 will be devoted to spine diseases thanks to the wonderful effort done by Dr. Alberto Alexandre from Treviso - Italy. The rest of the papers already sent and new to come will be published on 2020.
 
 The indexation of this journal is so fantastic, thanks to the University of Valencia’s Publication Service, that it is quickly compiled in all open …

The WFOT strikes back!

In October 2014 I was elected President of the WFOT. I want to thank here the support of Dr. Lamberto Re, Professor Nabil Mawsof and Dr. Mark Weisser, that encouraged to me assume this task. Six society members and 20 individual members from 10 more countries were awaiting to grow. Our bylaws, written 9 years before, were not adapted to the current worldwide situation of the ozone therapy; even inside WFOT, some situations needed formalization, so updating the bylaws was a mandatory task.
 
 With the huge help of Dr. Re, now President of the FIO, I was able to update the WFOT bylaws, so we started regularizing the minor issues inside WFOT and, together with Dr. Re, we both started…

Scientific approach for ozone absorption in blood during systemic indirect endovenous ozonetherapy

Introduction.
 Reading reference ozone books from Dra. Menendez, Dra. Viebhan, Dra. Borrelli and Dr. Bocci, proper timing for mixing ozone in blood during autohemotherapy is not calculated in a scientific way, having only an estimation of it based on changes in the blood color, more related to oxygen absorption than on ozone itself.
 
 Material and methods.
 We decided to reproduce a reduced model of great autohemotherapy or recently renamed as systemic indirect endovenous ozonotherapy (SIEVO) by the World Federation of Ozone Therapy – WFOT, using syringes to simplify the experiment. Our model consisted of a 20 mL syringe filled with 10 mL of blood withdrawn from healthy…