0000000000369942
AUTHOR
Nicolo' Vivona
showing 23 related works from this author
Trasformazioni eterocicliche di 1,2,4-ossadiazoli fluorurati in reazioni ANRORC-like
2008
Characterization of isomeric organic cations by Esi/MS: 3-alkyl-5-(4-N-methylpyridinium)-1,2,4-oxadiazole cations, 5-alkyl-3-(4-N-methylpyridinium)-1…
2005
Anrorc rearrangements of fluorinated 1,2,4-oxadiazoles as an expedient route to fluorinated heterocycles
2006
Composti eterociclici fluorurati. Un approccio fotochimico alla sintesi di chinazolin-4-oni
2004
Designing fluorous domains. Pyridinium salts bearing a perfluoroalkylated oxadiazole moiety
2005
Nuovi film elettrocromici
2008
Recent Advances in 1,2,4-Oxadiazole Chemistry
2005
Fluorinated heterocyclic compounds from ring-to-ring transformations of O-N bond containing azoles
2004
Sintesi one-pot di N-ossidi di 2-ammino-pirimidine fluorurate. Riarrangiamenti competitivi “four-atom side-chain” di 1,2,4-ossadiazoli
2005
Nuovi Riarrangiamenti Boulton-Katritzky di derivati 1,2,4-ossadiazolici contenenti un atomo di carbonio nucleofilo in catena laterale
2009
Experimental and DFT Studies on Competitive Heterocyclic Rearrangements. A Cascade Isoxazole-1,2,4-Oxadiazole-Oxazole Rearrangement
2009
The thermal rearrangements of 3-acylamino-5-methylisoxazoles 1 have been investigated under basic and neutral conditions and interpreted with the support of computational data. The density functional theory (DFT) study on the competitive routes available for the base-catalyzed thermal rearrangement of isoxazoles 1 showed that the Boulton-Katritzky (BK) rearrangement, producing the less stable 3-acetonyl- 1,2,4-oxadiazoles 5, is a much more favored process than either the migration-nucleophilic attack-cyclization (MNAC) or the ring contraction-ring expansion (RCRE). In turn, an increase in reaction temperature will promote the MNAC of oxadiazoles 5, producing the more stable 2-acylaminooxazo…
Studio dell’effetto dei sostituenti sul riarrangiamento fotoindotto di diaril-1,2,4-ossadiazoli in zeolite NaY
2008
Synthesis of trifluoromethylated 2-benzoyl- and 3-aminoimidazoles from ring rearrangement of 1,2,4-oxadiazole derivative
2008
Fluoroalkylated 2-ylamino-imidazoles have been synthesized by reaction of 3-amino-5-phenyl-1,2,4-oxadiazole with fluorinated b-dicarbonyl compounds and subsequent base-induced BoultoneKatritzky Rearrangement (BKR) of the isolated b-enaminocarbonyl intermediate. Alternatively, one-pot reactions performed in the presence of Montmorillonite K10 favoured the condensation at the 3-amino moiety of the oxadiazole and, in some cases, allowed the direct synthesis of 2-benzoylamino-imidazoles. Hydrolysis of 2-benzoylamino-imidazoles easily yielded fluorinated 2-amino-imidazoles targets.
Synthesis, Reactivity, Biological Activity and Applications of Fluorinated Oxadiazoles and Thiadiazoles
2014
A literature survey of the chemistry of fluorinated oxadiazoles and thiadiazoles is presented. The core part on synthetic procedures is given by type of heterocycle and includes recent developments up to the end of 2012. Reactivity is discussed when induced by the presence of the fluorinated moiety. Selected examples of bioactive compounds and applications are illustrated.
Sintesi di ossadiazoli fluorurati come nuovi Low molecular weight hydrogelators
2010
Microreattori fluorurati. Studio della reazione "ene" con ossigeno singoletto in zeolite NAY modificata con cationi fluoroorganici
2006
Fluoroarylation of hydroxylated molecules with 5-pentafluorophenyl-1,2,4-oxadiazoles
2005
Experimental and DFT studies on competitive heterocyclic rearrangements. part 2: A one-atom side-chain versus the classic three-atom side-chain (Boul…
2007
The experimental investigation of the base-catalyzed rearrangements of 3-acylamino-1,2,4-oxadiazoles evidenced a new reaction pathway which competes with the well-known ring-degenerate Boulton- Katritzky rearrangement (BKR). The new reaction consists of a one-atom side-chain rearrangement that is base-activated, occurs at a higher temperature than the BKR, and irreversibly leads to the corresponding 2-acylamino-1,3,4-oxadiazoles. An extensive DFT study is reported to elucidate the proposed reaction mechanism and to compare the three possible inherent routes: (i) the reversible three-atom side-chain ring-degenerate BKR, (ii) the ring contraction-ring expansion route (RCRE), and (iii) the one…