0000000000380849

AUTHOR

Berthold Rzany

showing 3 related works from this author

An 18-Month Follow-up, Randomized Comparison of Effectiveness and Safety of Two Hyaluronic Acid Fillers for Treatment of Moderate Nasolabial Folds

2016

Hyaluronic acid (HA) filler injection is a popular nonsurgical aesthetic procedure.To compare the effectiveness and safety of 2 hyaluronic acid fillers (HAEC and HARES) for treatment of moderate nasolabial folds (NLFs).This was an evaluator- and subject-blinded split-face study. HAEC or HARES was randomly assigned to the left or right NLF at baseline. Retreatment was performed after 9 months; follow-up extended to 18 months after baseline (9 months after retreatment). Effectiveness assessments included the Wrinkle Severity Rating Scale (WSRS) and subject preference. Safety assessments included adverse events (AEs) and local tolerability symptoms recorded by subjects during 3 weeks after tre…

AdultMalemedicine.medical_specialtyNasolabial FoldTime FactorsTreatment outcomeDermatology030230 surgerylaw.invention030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDouble-Blind MethodRandomized controlled triallawDermal FillersHyaluronic acidmedicineHumansHyaluronic AcidAgedbusiness.industryFollow up studiesPatient PreferenceGeneral MedicineMiddle AgedNasolabial foldPatient preferenceSkin AgingSurgeryTreatment Outcomemedicine.anatomical_structureMulticenter studychemistryRetreatmentFemaleSurgerybusinessFollow-Up StudiesMonth follow upDermatologic Surgery
researchProduct

Efficacy and safety of a new hyaluronic acid dermal filler in the treatment of severe nasolabial lines - 6-month interim results of a randomized, eva…

2011

Summary Background  Hyaluronic acid (HA) fillers are frequently used for the correction of facial soft tissue defects. Aim  To compare the efficacy and safety of a novel HA filler, HAE (Emervel Deep), with those of HAP (Restylane Perlane) in the treatment of severe nasolabial folds (NLF). Patients/Methods  A split-face, randomized and evaluator-blinded comparison study. Subjects were randomized to receive injection of HAE or HAP on their left or right NLF. Efficacy was evaluated based on the change in Wrinkle Severity Rating Scale (WSRS) from baseline. Local tolerability was assessed based on subject diary during the first 3 weeks after injection. Adverse events were also evaluated. Results…

medicine.medical_specialtyErythemabusiness.industrySoft tissueDermatologylaw.inventionSurgeryClinical trialRandomized controlled trialTolerabilitylawEdemamedicinemedicine.symptomAdverse effectbusinessWrinkleJournal of Cosmetic Dermatology
researchProduct

Efficacy and safety of a new hyaluronic acid dermal filler in the treatment of moderate nasolabial folds: 6-month interim results of a randomized, ev…

2011

Hyaluronic acid (HA) fillers such as Restylane(®) are frequently used for the correction of facial soft tissue defects.To compare the efficacy and safety of a novel HA filler, Emervel(®) Classic, with those of Restylane in the treatment of moderate nasolabial folds.This was a split-face, randomized and evaluator-blinded comparison study. Subjects were randomized to receive an injection of Emervel Classic or Restylane on their left or right side. Efficacy was evaluated based on the change in Wrinkle Severity Rating Score (WSRS) from baseline. Local tolerability was assessed based on subject diary, which recorded the severity of erythema, oedema/swelling, bruising, pain/tenderness and pruritu…

AdultMalemedicine.medical_specialtyErythemaRestylaneCosmetic TechniquesDermatologylaw.inventionchemistry.chemical_compoundRandomized controlled triallawHyaluronic acidSubject DiarymedicineHumansSingle-Blind MethodHyaluronic AcidWrinklebusiness.industrySoft tissueMiddle AgedSkin AgingSurgerychemistryTolerabilityFemaleSurgerymedicine.symptombusinessJournal of Cosmetic and Laser Therapy
researchProduct